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Biology Concepts and Investigations 3rd Edition Hoefnagels Test Bank

ISBN-13: 978-0073525549

ISBN-10: 0073525545

 

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Biology Concepts and Investigations 3rd Edition Hoefnagels Test Bank

ISBN-13: 978-0073525549

ISBN-10: 0073525545

 

 

 

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Free Nursing Test Questions:

Chapter 008 – DNA Replication, Mitosis and the Cell Cycle

 

Multiple Choice Questions

1. The molecule that controls the synthesis of proteins and copies itself for the next generation of cells is:

A. ATP synthase

 

B. DNA

 

C. RNA

 

D. NAD

 

E. FAD

 

2. The scientist (scientists) that discovered that bacteria can transfer genetic information is (are):

A. Hershey and Chase

 

B. Chargaff

 

C. Griffith

 

D. Watson and Crick

 

E. Wilkins and Franklin

 

3. The scientist (scientists) that first showed that protein was not the genetic information transferred by bacteria by using enzymes to digest protein is (are):

A. Griffith

 

B. Hershey and Chase

 

C. Watson and Crick

 

D. Avery and Macleod

 

E. Wilkins and Franklin

 

4. The scientist (scientists) that confirmed DNA was the genetic information by working with bacteria that infect viruses is (are):

A. Griffith

 

B. Hershey and Chase

 

C. Avery and Macleod

 

D. Watson and Crick

 

E. Chargaff

 

5. The scientist (scientists) that showed that DNA contained equal amounts of certain nitrogen bases is (are):

A. Chargaff

 

B. Griffith

 

C. Hershey and Chase

 

D. Avery and Macleod

 

E. Wilkins and Franklin

 

6. The scientist (scientists) that used x-ray diffraction to help reveal the structure of DNA is (are):

A. Watson and Crick

 

B. Hershey and Chase

 

C. Avery and Macleod

 

D. Chargaff

 

E. Wilkins and Franklin

 

7. The scientist (scientists) that was (were) given credit for first determining the structure of DNA by building a ball and stick model is (are):

A. Hershey and Chase

 

B. Watson and Crick

 

C. Avery and Macleod

 

D. Chargaff

 

E. Griffith

 

8. The bacteria that Griffith experimented with were termed “R” and “S” bacteria because:

A. Of the way they grew on artificial media

 

B. The “R” bacteria formed rough appearing colonies

 

C. The “S” bacteria formed smooth appearing colonies

 

D. All are correct

 

9. The reason that the type “S” bacteria could infect mice and cause pneumonia was because:

A. They had flagella as a means of movement

 

B. They reproduced much faster than type “R” bacteria

 

C. They produced a polysaccharide capsule (coat)

 

D. All are correct

 

10. Most bacteriophages consist of only a _______________ coat and a ____________________ core.

A. Lipid, protein

 

B. Polysaccharide, nucleic acid

 

C. Protein, lipid

 

D. Protein, nucleic acid

 

E. Polysaccharide, protein

 

11. Hershey and Chase showed that the virus T4:

A. Injects protein into a bacterium

 

B. Injects polysaccharide into a bacterium

 

C. Injects DNA into a bacterium

 

D. Injects protein and DNA into a bacterium

 

E. Injects RNA into a bacterium

 

12. The building block of nucleic acids is a(an):

A. Nucleotide

 

B. Amino acid

 

C. Glucose molecule

 

D. Glycerol molecule

 

E. None of the above are correct

 

13. DNA contains equal amounts of adenine and:

A. Uracil

 

B. Guanine

 

C. Thymine

 

D. Cytosine

 

E. Threonine

 

14. DNA contains equal amounts of cytosine and:

A. Thymine

 

B. Uracil

 

C. Guanine

 

D. Adenine

 

E. Valine

 

15. The four nitrogen bases that are found in the different nucleotides of DNA are:

A. Adenine, thymine, cytosine, uracil

 

B. Uracil, adenine, cytosine, guanine

 

C. Uracil, cytosine, guanine, thymine

 

D. Adenine, thymine, cytosine, guanine

 

E. None are correct

 

16. DNA’s sugar-phosphate backbones are joined with:

A. Ionic bonds

 

B. Hydrogen bonds

 

C. Weak chemical bonds

 

D. Covalent bonds

 

17. Strands of DNA are joined by:

A. Hydrogen bonds

 

B. Covalent bonds

 

C. Ionic bonds

 

D. Phosphodiester bonds

 

18. The DNA nitrogen bases that are pyrimidines are:

A. Cytosine and guanine

 

B. Uracil and cytosine

 

C. Thymine and cytosine

 

D. Thymine and adenine

 

E. Uracil and thymine

 

19. The DNA nitrogen bases that are purines are:

A. Adenine and thymine

 

B. Adenine and uracil

 

C. Guanine and thymine

 

D. Guanine and cytosine

 

E. Adenine and guanine

 

20. Pyrimidine bases have a __________ __________ structure:

A. Single, ring

 

B. Single, triangle

 

C. Double, ring

 

D. Double, triangle

 

E. Triple, ring

 

21. Purine bases have a _________ ___________ structure:

A. Single, ring

 

B. Single, triangle

 

C. Double, triangle

 

D. Double, ring

 

E. Triple, ring

 

22. The genome of an organism is all of its:

A. Proteins

 

B. RNA

 

C. Characteristics

 

D. Genetic material

 

E. All are correct

 

23. In eukaryotic cells DNA is found in the:

A. Nucleus

 

B. Chloroplasts

 

C. Mitochondria

 

D. All are correct

 

24. A human heart cell contains ___ chromosomes.

A. 2

 

B. 23

 

C. 46

 

D. 4

 

E. 16

 

25. Which of the following is found in a molecule of DNA?

A. Deoxyribose

 

B. Ribose

 

C. Uracil

 

D. Amino acid

 

E. A sulfur containing group

 

26. A sequence of DNA nucleotides coding for a specific protein or RNA molecule is a:

A. Genome

 

B. Chromosome

 

C. Gene

 

D. All of the above are correct

 

E. None of the above are correct

 

27. The 3′ and 5′ designations refer to the numbers that chemists assign to the:

A. Hydrogen atoms of deoxyribose

 

B. Oxygen atoms of deoxyribose

 

C. Carbon atoms in the nitrogen bases

 

D. Nitrogen atoms in the nitrogen bases

 

E. Carbon atoms of deoxyribose

 

28. The process by which DNA reproduces itself is:

A. Protein synthesis

 

B. Aerobic respiration

 

C. Replication

 

D. Substrate-phosphorylation

 

E. Photosynthesis

 

29. DNA replication is:

A. Conservative

 

B. A one-step process

 

C. Semi-conservative

 

D. Not carried out by enzymes

 

E. Not carried out in prokaryotic cells

 

30. The enzyme that unwinds DNA is:

A. Helicase

 

B. Primase

 

C. DNA polymerase

 

D. ATP synthase

 

E. Ligase

 

31. The enzyme that joins Okazaki fragments is:

A. Primase

 

B. DNA polymerase

 

C. Ligase

 

D. ATP synthase

 

E. Helicase

 

32. The enzyme that builds a short complementary piece of RNA at the start of each DNA segment to be replicated is:

A. DNA polymerase

 

B. Primase

 

C. ATP synthase

 

D. Ligase

 

E. Helicase

 

33. The enzyme that adds nucleotides to form new strands of DNA is:

A. Primase

 

B. ATP synthase

 

C. Ligase

 

D. Helicase

 

E. DNA polymerase

 

34. Mutations may be caused by:

A. Errors in replication

 

B. Exposure to radiation

 

C. Exposure to chemicals

 

D. Breakage of chromosomes

 

E. All are correct

 

35. People with xeroderma pigmentosum (XP) are at greater risk of skin cancer because:

A. They lack proteins that would repair the damage from exposure to ultraviolet radiation

 

B. They have fewer layers of skin than normal

 

C. They do not produce pigments

 

D. Their skin cells do not reproduce

 

E. All are correct

 

36. The polymerase chain reaction:

A. Doubles a region of DNA each cycle

 

B. Is used to transfer DNA into a cell

 

C. Makes a single copy of a region of DNA

 

D. Is used to determine the sequence of a region of DNA

 

E. All are correct

 

37. The scientist who developed DNA sequencing is:

A. Watson

 

B. Chargaff

 

C. Sanger

 

D. Avery

 

E. Hershey

 

38. Apoptosis is also called:

A. Replication

 

B. Mitosis

 

C. Programmed cell death

 

D. The cell cycle

 

E. Programmed cellular reproduction

 

39. Before a cell divides, it must first duplicate its entire:

A. Cytoplasmic contents

 

B. Cell membrane structure

 

C. Array of enzymes

 

D. Genome

 

E. All are correct

 

40. A discreet package of DNA and associated proteins in eukaryotes is a:

A. Chromosome

 

B. Nucleus

 

C. Ribosome

 

D. Golgi body

 

E. Centriole

 

41. A micron is:

A. One tenth (.1) of a meter

 

B. One thousandth (.001) of a meter

 

C. One millionth (.000001) of a meter

 

D. One hundredth (.01) of a meter

 

E. One thousand meters

 

42. A nucleosome consists of:

A. A stretch of DNA and histones

 

B. A stretch of DNA

 

C. An RNA molecule

 

D. A ribosome and RNA

 

E. Histones

 

43. Eukaryotic chromosomes become microscopically visible before cell division because:

A. They become less tightly wound

 

B. They become more tightly wound

 

C. They increase in length

 

D. They become more tightly wound and increase in length

 

E. They become less tightly wound and increase in length

 

44. One of two identical attached copies of a replicated chromosome defines the term:

A. Centromere

 

B. Chromatin

 

C. Chromosome

 

D. Nucleosome

 

E. Chromatid

 

45. A part of a chromosome that attaches sister chromatids to each other defines the term:

A. Chromatin

 

B. Nucleosome

 

C. Centromere

 

D. Histone

 

E. None of the above are correct

 

46. DNA and associated proteins in the nucleus defines the term:

A. Centromere

 

B. Nucleosome

 

C. Histone

 

D. Chromatin

 

E. Chromosome

 

47. A discrete continuous molecule of DNA wrapped around protein defines the term:

A. Nucleosome

 

B. Chromosome

 

C. Centromere

 

D. Histone

 

E. Genome

 

48. “Sister chromatids” are:

A. Genetically identical and attached to each other at centromere

 

B. Genetically different and attached to each other at centromere

 

C. Genetically different

 

D. Genetically identical

 

E. Attached to each other at centromere

 

49. A cell with two full sets of chromosomes would be termed a _______________ cell.

A. Haploid

 

B. Sister

 

C. Somatic

 

D. Diploid

 

E. Germ

 

50. A cell with one set of chromosomes would be termed a ________________ cell.

A. Diploid

 

B. Sister

 

C. Somatic

 

D. None of the above are correct

 

E. Haploid

 

51. The pair of unmatched chromosomes in humans:

A. Are the sex chromosomes

 

B. Are the “X” and “Y” chromosomes

 

C. Determine sex (gender) of humans

 

D. Contain different genes

 

E. All are correct

 

52. The process by which a sperm cell combines with an egg cell is:

A. Fertilization

 

B. Recombination

 

C. Replication

 

D. Mitosis

 

E. Germination

 

53. If a sperm cell combines with an egg cell the result is a:

A. Diploid cell

 

B. Gamete

 

C. Haploid cell

 

D. Duplicated chromosome

 

E. Gametophyte

 

54. An example of a haploid cell is:

A. A skin cell

 

B. A sperm cell

 

C. A zygote

 

D. A stem cell

 

E. All are correct

 

55. In humans, specialized cells that produce gametes are:

A. Germ cells

 

B. Somatic cells

 

C. Sperm cells

 

D. Egg cells

 

E. All are correct

 

56. In humans, cells that do not produce gametes are collectively called:

A. Sperm cells

 

B. Egg cells

 

C. Somatic cells

 

D. Germ cells

 

E. All are correct

 

57. Mitosis is used for all of the following except:

A. Repair of damaged cells

 

B. Growth of an organism

 

C. Asexual reproduction

 

D. Formation of gametes

 

E. Production of genetically identical daughter cells

 

58. Meiosis is a process used for:

A. Repair of damaged cells

 

B. Growth of an organism

 

C. Asexual reproduction

 

D. Production of stem cells

 

E. Production of gametes

 

59. Meiosis is a process used for:

A. Asexual reproduction

 

B. Growth of an organism

 

C. Production of gametes

 

D. Repair of damaged cells

 

E. All are correct

 

60. Immature cells that retain the potential to develop into multiple cell types are:

A. Germ cells

 

B. Somatic cells

 

C. Stem cells

 

D. Nerve cells

 

E. All are correct

 

61. The two main stages of the cell cycle are:

A. Interphase and cytokinesis

 

B. Interphase and mitosis

 

C. Mitosis and cytokinesis

 

D. Interphase and prophase

 

E. Mitosis and meiosis

 

62. The splitting of a cell into two daughter cells in the cell cycle is:

A. Mitosis

 

B. Interphase

 

C. Cytokinesis

 

D. Metaphase

 

E. Anaphase

 

63. The division of the nucleus during the cell cycle is:

A. Mitosis

 

B. Interphase

 

C. Synthesis

 

D. Cytokinesis

 

E. Replication

 

64. The replication of DNA during the cell cycle occurs during:

A. Mitosis

 

B. Cytokinesis

 

C. Prophase

 

D. Telophase

 

E. Interphase

 

65. The correct sequence for the phases of the cell cycle is:

A. Interphase – prophase – prometaphase – metaphase – anaphase – telophase

 

B. Prophase – prometaphase – metaphase – anaphase – telophase

 

C. Prophase – prometaphase – anaphase – metaphase – telophase

 

D. Interphase – prometaphase – prophase – metaphase – anaphase – telophase

 

E. Metaphase – anaphase – interphase – prophase – telophase

 

66. The correct sequence for the phases of mitosis is:

A. Prometaphase – prophase – metaphase – anaphase – telophase

 

B. Interphase – prophase – metaphase – anaphase – telophase

 

C. Interphase – metaphase – anaphase – prophase – telophase

 

D. Prophase – metaphase – prometaphase – anaphase – telophase

 

E. Prophase – prometaphase – metaphase – anaphase – telophase

 

67. The portion of the cytoskeleton that enables the chromosomes to be separated equally into two sets is the:

A. Golgi body

 

B. Centromere

 

C. Centrosome

 

D. Mitotic spindle

 

E. Kinetochore

 

68. The structure that organizes the protein subunits of the mitotic spindle is the:

A. Centromere

 

B. Kinetochore

 

C. Centrosome

 

D. Cytoskeleton

 

E. Microfilaments

 

69. The proteins that attach chromosomes to the mitotic spindle are:

A. Kinetochores

 

B. Chromatids

 

C. Nucleosomes

 

D. Centromeres

 

E. Histones

 

70. The phase of mitosis in which the nuclear envelope breaks into small pieces is:

A. Prophase

 

B. Metaphase

 

C. Anaphase

 

D. Prometaphase

 

E. Telophase

 

71. The phase of mitosis in which the centromeres split and sister chromatids are pulled to opposite poles of the cell is:

A. Prophase

 

B. Anaphase

 

C. Prometaphase

 

D. Metaphase

 

E. Telophase

 

72. The phase of mitosis in which the chromosomes are aligned along the equator of the cell is:

A. Metaphase

 

B. Prophase

 

C. Prometaphase

 

D. Anaphase

 

E. Telophase

 

73. The phase of mitosis in which the nuclear envelope reforms is:

A. Prophase

 

B. Prometaphase

 

C. Metaphase

 

D. Anaphase

 

E. Telophase

 

74. The phase of mitosis in which the chromosomes condense and centrosomes move to opposite poles of the cell is:

A. Prometaphase

 

B. Metaphase

 

C. Prophase

 

D. Anaphase

 

E. Telophase

 

75. The first sign of cytokinesis in an animal cell is the formation of a:

A. Cell plate

 

B. Cleavage furrow

 

C. Cell wall

 

D. Nucleolus

 

E. Nuclear envelope

 

76. The first sign of cytokinesis in a plant cell is the formation of a:

A. Nuclear envelope

 

B. Nucleolus

 

C. Cleavage furrow

 

D. Cell plate

 

E. Spindle fiber

 

77. If scientists could inactivate telomerase in specific cells, the primary reason for this would most likely be the stopping of:

A. Aerobic respiration

 

B. Meiosis

 

C. Aging of cells

 

D. The formation of cancer

 

E. All are correct

 

78. If scientists could increase telomerase production in specific cells, the primary reason for this would most likely be the stopping of:

A. Aging of cells

 

B. Aerobic respiration

 

C. Meiosis

 

D. Cancer cell formation

 

E. All are correct

 

79. In an asexual life cycle, cells reproduce by:

A. Meiosis

 

B. Fertilization

 

C. Meiosis and Fertilization

 

D. Mitosis

 

E. All are correct

 

80. In a sexual life cycle, a zygote grows to an adult by:

A. Meiosis

 

B. Fertilization

 

C. Meiosis and Fertilization

 

D. Mitosis

 

E. All are correct

 

81. How does the space between our fingers arise?

A. The cells die by necrosis

 

B. Mitosis of the cells is blocked

 

C. The cells die by apoptosis

 

D. Meiosis of the cells is blocked

 

E. The cells become part of the fingers

 

82. If one strand of a DNA molecule has the base sequence of 5′ ATGTGCC 3′ the complementary strand of DNA will read:

A. 3′ ATGTGCC 5′

 

B. 3′ TACACGG 5′

 

C. 3′ UACACGG 5′

 

D. 3′ CGTGTAA 5′

 

E. 3′ GGCACAT 5′

 

83. If one strand of a DNA molecule has the base sequence of 5′ CGGCATTA 3′ the complementary strand of DNA will read:

A. 3′ CGGCATTA 5′

 

B. 3′ ATTACGGC 5′

 

C. 3′ GCCGTUUT 5′

 

D. 3′ GCCGTAAT 5′

 

E. 3′ TAATGCCG 5′

 

84. If a mutation causes the “T” base in the base sequence 5′ AGTCCG 3′ to be read as a “G” base, DNA replication of the mutated sequence will read:

A. 3′ TCCGGC 5′

 

B. 3′ AGGCCG 5′

 

C. 3′ CTTAAT 5′

 

D. 3′ UCCGGC 5′

 

E. 3′ AGTCCG 5′

 

85. If a mutation causes the “G” base in the base sequence 5′ AATGAC 3′ to be read as a “T” base, DNA replication of the mutated sequence will read:

A. 3′ AATTAC 5′

 

B. 3′ TTCCTG 5′

 

C. 3′ GGCCGT 5′

 

D. 3′ TTAATG 5′

 

E. 3′ AATGAC 5′

 

86. Why does a replication fork have a leading and lagging strand?

A. Because DNA synthesis always goes from 3′ to 5′

 

B. Because DNA synthesis can grow off of either the 3′ or 5′ end

 

C. Because DNA synthesis always goes from 5′ to 3′

 

D. To slow down DNA synthesis to make time for mitosis

 

E. To slow down DNA synthesis to make time for the production of primers

 

87. When DNA replicates:

A. The original DNA is not affected and a new double-stranded DNA is made from two new strands of DNA

 

B. One strand of the original DNA ends up in each of the new DNA molecules

 

C. The original DNA unwinds, and multiple copies of a region are transcribed before the DNA closes back up

 

D. Transcription factors determine where to begin DNA replication

 

E. A cell that was diploid (2N) will now be tetraploid (4N)

 

88. Based on the structure of the DNA backbone you would predict the surface of histones to be:

A. Negatively charged

 

B. Positively charged

 

C. Neutral

 

D. Hydrophobic

 

E. Hydrophilic

 

89. A cell would pack its DNA as chromatin in preparation for:

A. Replication

 

B. Transcription

 

C. Translation

 

D. Splicing

 

E. Mitosis

 

90. The chemotherapy drug taxol inhibits microtubule function. A cell treated with taxol would become stuck in which phase?

A. Prophase

 

B. Metaphase

 

C. Anaphase

 

D. Telophase

 

E. Cytokinesis

 

91. Why don’t plant cells form a cleavage furrow during cytokinesis?

A. Because they don’t have a cell membrane

 

B. Because their cells don’t divide after mitosis, but become one larger cell with multiple nuclei

 

C. Because they have a cell wall

 

D. Because they don’t have a nucleus

 

E. All are correct

 

92. By ignoring a checkpoint in the cell cycle, a cancer cell may:

A. Divide after mutations are fixed

 

B. Divide before its DNA is completely replicated

 

C. Condense its chromosomes before mitosis

 

D. Align chromosomes on the equator of the cell during metaphase

 

E. Pull chromosomes apart during anaphase

 

93. In order for a cell to become cancerous, oncogenes must be ___ and tumor suppressors ___.

A. Inactivated, activated

 

B. Both activated

 

C. Both inactivated

 

D. Activated, inactivated

 

94. The enzyme telomerase adds DNA to the ends of chromosomes. Why would cancer cells express high levels of telomerase?

A. As telomeres get shorter a cell loses the ability to divide

 

B. The longer a chromosome is, the more genes a cancer cell will have

 

C. Longer chromosomes have more active genes

 

D. To allow the chromosomes to be replicated more rapidly

 

E. Telomerase is a tumor suppressor

 

95. Stem cells from a blastocyst

A. Can only produce certain types of cells

 

B. Can form any type of cell in the body

 

C. Cannot survive outside of the blastocyst

 

D. Cannot be formed by in vitro fertilization

 

E. Can be obtained from adult tissues

 

96. Stem cells from an adult

A. Can only produce certain types of cells

 

B. Can form any type of cell in the body

 

C. Cannot survive outside of the adult

 

D. Can be formed by in vitro fertilization

 

E. Are obtained from a blastocyst

 

97. In cloning the sheep Dolly, a nucleus was implanted into an egg that had its nucleus removed. The result of this somatic cell transfer was a ____ egg.

A. Haploid

 

B. Fertilized

 

C. Embryonic

 

D. Diploid

 

E. Tetraploid

 

98. For the polymerase chain reaction (PCR) to work, the Taq _______ must be heat stable to avoid denaturation.

A. DNA polymerase

 

B. RNA polymerase

 

C. Ribosome

 

D. Primase

 

E. DNA

 

99. Why would a cancer cell need to induce angiogenesis?

A. Because cells in the center of a tumor become too far from blood vessels

 

B. It is the first step in metastasis

 

C. To avoid checkpoints in the cell cycle

 

D. It would activate oncogenes

 

E. It would inactivate tumor suppressors

 

100. Cancer cells secrete molecules that stimulate endothelial cells to divide by first:

A. Passing through the S phase checkpoint

 

B. Lining chromosomes up on the equator of the cell

 

C. Pulling chromosomes apart toward the poles of the cell

 

D. Passing through the G1 checkpoint

 

E. Passing through the G2 checkpoint

 

101. Why did the researchers induce cancer in mice by injecting cancer cells, instead of just doing the experiment on isolated cancer cells in culture?

A. Cancer cells can go through angiogenesis in culture

 

B. Cancer cells cannot be grown outside of the body in culture

 

C. Angiogenesis occurs in a whole organism

 

D. Tumor suppressors are only active in whole tumors

 

E. Oncogenes are only active in whole tumors

 

102. Cyclophosphamide forms crosslinks between the two strands of DNA in a chromosome. How would this be effective in chemotherapy?

A. It would block splicing

 

B. It would block DNA replication

 

C. It would activate oncogenes

 

D. It would inactivate tumor suppressors

 

E. It would block metaphase

 

103. What hypothesis were the researchers testing by treating tumors with endostatin and cyclophosphamide?

A. Because endostatin works on endothelial cells, natural selection for resistance will not occur in tumor cells

 

B. Because endostatin works on tumor cells, natural selection for resistance will not occur in endothelial cells

 

C. Because cyclophosphamide works on endothelial cells, natural selection for resistance will not occur in tumor cells

 

D. Because cyclophosphamide works on tumor cells, natural selection for resistance will not occur in endothelial cells

 

   

 

104. What is the dependent variable in figure 8.26?

A. The volume of the tumor in humans

 

B. Treatment days

 

C. Treatment with endostatin

 

D. Treatment with cyclophosphamide

 

E. The volume of the tumor in mice

 

105. What did the researchers conclude from figure 8.26a?

A. Endostatin shrunk tumors but resistance developed

 

B. Cyclophosphamide delayed the growth of tumors without development of resistance

 

C. Endostatin shrunk tumors without development of resistance

 

D. Cyclophosphamide delayed the growth of tumors but resistance developed

 

E. Tumors in untreated cells shrank in size

 

106. What did the researchers conclude from figure 8.26b?

A. Cyclophosphamide delayed the growth of tumors but resistance developed

 

B. Endostatin shrunk tumors without development of resistance

 

C. Endostatin shrunk tumors but resistance developed

 

D. Cyclophosphamide delayed the growth of tumors without development of resistance

 

E. Tumors in untreated cells shrank in size

 

107. Endostatin is a 184-amino acid protein. How could enough endostatin be produced to use as a drug?

A. The endostatin gene would be cloned and injected into a patient to produce endostatin

 

B. Endostatin protein would be injected into bacteria to produce more endostatin

 

C. The endostatin gene would be cloned and injected into bacteria to produce endostatin

 

D. Inject endostatin mRNA into a patient to produce endostatin

 

E. Inject endostatin antisense RNA into a bacteria to produce endostatin

 

108. Endostatin is a 184-amino acid protein that only affects endothelial cells. What is the best explanation for this observation?

A. Endothelial cells produce endostatin

 

B. Endostatin can diffuse across the membrane of endothelial cells

 

C. Only endothelial cells are exposed to endostatin

 

D. Endothelial cells have a receptor on their cell membrane for endostatin

 

E. Endostatin enters endothelial cells by endocytosis

 

 

True / False Questions

109. A bacteriophage infects a bacterial cell by injecting nucleic acid into the bacterium.

True    False

 

110. Variants or alternate forms of a gene are called alleles:

True    False

 

111. Any change in a cell’s DNA sequence is a mutation.

True    False

 

112. Change in a cell’s DNA sequence is a regular occurrence in the process of replication.

True    False

 

113. Each newly replicated molecule of DNA contains one conserved strand from the original DNA molecule.

True    False

 

114. The process used to determine the order of bases in DNA is polymerase chain reaction.

True    False

 

115. The process used to determine the order of bases in DNA is DNA sequencing.

True    False

 

116. The process used to rapidly produce DNA sequences of interest is polymerase chain reaction.

True    False

 

117. The process used to rapidly produce DNA sequences of interest is DNA sequencing.

True    False

 

118. A replicated chromosome consists of two “sister chromatids.”

True    False

 

119. Replication takes place during the G1 phase of interphase.

True    False

 

120. During cytokinesis of a plant cell, the cell divides by forming a cleavage furrow.

True    False

 

121. During the cell cycle there are several checkpoints that ensure that the cell cycle is proceeding correctly.

True    False

 

122. Cells that produce telomerase can usually divide many more times than cells that do not produce telomerase.

True    False

 

123. If scientists could stimulate telomerase production in cancer cells, this would most likely help stop the cancerous growth.

True    False

 

124. An abnormal mass of tissue is a tumor.

True    False

 

125. If a cancer metastasizes, its cells travel through the blood stream and colonize other areas of the body.

True    False

 

 

 

Chapter 008 – DNA Replication, Mitosis and the Cell Cycle Key
 

Multiple Choice Questions

1. The molecule that controls the synthesis of proteins and copies itself for the next generation of cells is:

A. ATP synthase

 

B. DNA

 

C. RNA

 

D. NAD

 

E. FAD

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

2. The scientist (scientists) that discovered that bacteria can transfer genetic information is (are):

A. Hershey and Chase

 

B. Chargaff

 

C. Griffith

 

D. Watson and Crick

 

E. Wilkins and Franklin

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.00.01 Explain how cells divide to give rise to identical cells.
SECTION: 08.01
TOPIC: DNA Replication
 

 

3. The scientist (scientists) that first showed that protein was not the genetic information transferred by bacteria by using enzymes to digest protein is (are):

A. Griffith

 

B. Hershey and Chase

 

C. Watson and Crick

 

D. Avery and Macleod

 

E. Wilkins and Franklin

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.00.01 Explain how cells divide to give rise to identical cells.
SECTION: 08.01
TOPIC: DNA Replication
 

 

4. The scientist (scientists) that confirmed DNA was the genetic information by working with bacteria that infect viruses is (are):

A. Griffith

 

B. Hershey and Chase

 

C. Avery and Macleod

 

D. Watson and Crick

 

E. Chargaff

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.00.01 Explain how cells divide to give rise to identical cells.
SECTION: 08.01
TOPIC: DNA Replication
 

 

5. The scientist (scientists) that showed that DNA contained equal amounts of certain nitrogen bases is (are):

A. Chargaff

 

B. Griffith

 

C. Hershey and Chase

 

D. Avery and Macleod

 

E. Wilkins and Franklin

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.00.01 Explain how cells divide to give rise to identical cells.
SECTION: 08.01
TOPIC: DNA Replication
 

 

6. The scientist (scientists) that used x-ray diffraction to help reveal the structure of DNA is (are):

A. Watson and Crick

 

B. Hershey and Chase

 

C. Avery and Macleod

 

D. Chargaff

 

E. Wilkins and Franklin

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.00.01 Explain how cells divide to give rise to identical cells.
SECTION: 08.01
TOPIC: DNA Replication
 

 

7. The scientist (scientists) that was (were) given credit for first determining the structure of DNA by building a ball and stick model is (are):

A. Hershey and Chase

 

B. Watson and Crick

 

C. Avery and Macleod

 

D. Chargaff

 

E. Griffith

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.00.01 Explain how cells divide to give rise to identical cells.
SECTION: 08.01
TOPIC: DNA Replication
 

 

8. The bacteria that Griffith experimented with were termed “R” and “S” bacteria because:

A. Of the way they grew on artificial media

 

B. The “R” bacteria formed rough appearing colonies

 

C. The “S” bacteria formed smooth appearing colonies

 

D. All are correct

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.00.01 Explain how cells divide to give rise to identical cells.
SECTION: 08.01
TOPIC: DNA Replication
 

 

9. The reason that the type “S” bacteria could infect mice and cause pneumonia was because:

A. They had flagella as a means of movement

 

B. They reproduced much faster than type “R” bacteria

 

C. They produced a polysaccharide capsule (coat)

 

D. All are correct

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

10. Most bacteriophages consist of only a _______________ coat and a ____________________ core.

A. Lipid, protein

 

B. Polysaccharide, nucleic acid

 

C. Protein, lipid

 

D. Protein, nucleic acid

 

E. Polysaccharide, protein

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

11. Hershey and Chase showed that the virus T4:

A. Injects protein into a bacterium

 

B. Injects polysaccharide into a bacterium

 

C. Injects DNA into a bacterium

 

D. Injects protein and DNA into a bacterium

 

E. Injects RNA into a bacterium

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

12. The building block of nucleic acids is a(an):

A. Nucleotide

 

B. Amino acid

 

C. Glucose molecule

 

D. Glycerol molecule

 

E. None of the above are correct

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

13. DNA contains equal amounts of adenine and:

A. Uracil

 

B. Guanine

 

C. Thymine

 

D. Cytosine

 

E. Threonine

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

14. DNA contains equal amounts of cytosine and:

A. Thymine

 

B. Uracil

 

C. Guanine

 

D. Adenine

 

E. Valine

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

15. The four nitrogen bases that are found in the different nucleotides of DNA are:

A. Adenine, thymine, cytosine, uracil

 

B. Uracil, adenine, cytosine, guanine

 

C. Uracil, cytosine, guanine, thymine

 

D. Adenine, thymine, cytosine, guanine

 

E. None are correct

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

16. DNA’s sugar-phosphate backbones are joined with:

A. Ionic bonds

 

B. Hydrogen bonds

 

C. Weak chemical bonds

 

D. Covalent bonds

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

17. Strands of DNA are joined by:

A. Hydrogen bonds

 

B. Covalent bonds

 

C. Ionic bonds

 

D. Phosphodiester bonds

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

18. The DNA nitrogen bases that are pyrimidines are:

A. Cytosine and guanine

 

B. Uracil and cytosine

 

C. Thymine and cytosine

 

D. Thymine and adenine

 

E. Uracil and thymine

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

19. The DNA nitrogen bases that are purines are:

A. Adenine and thymine

 

B. Adenine and uracil

 

C. Guanine and thymine

 

D. Guanine and cytosine

 

E. Adenine and guanine

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

20. Pyrimidine bases have a __________ __________ structure:

A. Single, ring

 

B. Single, triangle

 

C. Double, ring

 

D. Double, triangle

 

E. Triple, ring

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

21. Purine bases have a _________ ___________ structure:

A. Single, ring

 

B. Single, triangle

 

C. Double, triangle

 

D. Double, ring

 

E. Triple, ring

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

22. The genome of an organism is all of its:

A. Proteins

 

B. RNA

 

C. Characteristics

 

D. Genetic material

 

E. All are correct

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

23. In eukaryotic cells DNA is found in the:

A. Nucleus

 

B. Chloroplasts

 

C. Mitochondria

 

D. All are correct

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

24. A human heart cell contains ___ chromosomes.

A. 2

 

B. 23

 

C. 46

 

D. 4

 

E. 16

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

25. Which of the following is found in a molecule of DNA?

A. Deoxyribose

 

B. Ribose

 

C. Uracil

 

D. Amino acid

 

E. A sulfur containing group

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

26. A sequence of DNA nucleotides coding for a specific protein or RNA molecule is a:

A. Genome

 

B. Chromosome

 

C. Gene

 

D. All of the above are correct

 

E. None of the above are correct

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

27. The 3′ and 5′ designations refer to the numbers that chemists assign to the:

A. Hydrogen atoms of deoxyribose

 

B. Oxygen atoms of deoxyribose

 

C. Carbon atoms in the nitrogen bases

 

D. Nitrogen atoms in the nitrogen bases

 

E. Carbon atoms of deoxyribose

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

28. The process by which DNA reproduces itself is:

A. Protein synthesis

 

B. Aerobic respiration

 

C. Replication

 

D. Substrate-phosphorylation

 

E. Photosynthesis

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.02 Explain what features of DNA allow semiconservative replication to occur.
SECTION: 08.02
TOPIC: DNA Replication
 

 

29. DNA replication is:

A. Conservative

 

B. A one-step process

 

C. Semi-conservative

 

D. Not carried out by enzymes

 

E. Not carried out in prokaryotic cells

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.02 Explain what features of DNA allow semiconservative replication to occur.
SECTION: 08.02
TOPIC: DNA Replication
 

 

30. The enzyme that unwinds DNA is:

A. Helicase

 

B. Primase

 

C. DNA polymerase

 

D. ATP synthase

 

E. Ligase

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

31. The enzyme that joins Okazaki fragments is:

A. Primase

 

B. DNA polymerase

 

C. Ligase

 

D. ATP synthase

 

E. Helicase

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

32. The enzyme that builds a short complementary piece of RNA at the start of each DNA segment to be replicated is:

A. DNA polymerase

 

B. Primase

 

C. ATP synthase

 

D. Ligase

 

E. Helicase

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

33. The enzyme that adds nucleotides to form new strands of DNA is:

A. Primase

 

B. ATP synthase

 

C. Ligase

 

D. Helicase

 

E. DNA polymerase

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

34. Mutations may be caused by:

A. Errors in replication

 

B. Exposure to radiation

 

C. Exposure to chemicals

 

D. Breakage of chromosomes

 

E. All are correct

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

35. People with xeroderma pigmentosum (XP) are at greater risk of skin cancer because:

A. They lack proteins that would repair the damage from exposure to ultraviolet radiation

 

B. They have fewer layers of skin than normal

 

C. They do not produce pigments

 

D. Their skin cells do not reproduce

 

E. All are correct

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

36. The polymerase chain reaction:

A. Doubles a region of DNA each cycle

 

B. Is used to transfer DNA into a cell

 

C. Makes a single copy of a region of DNA

 

D. Is used to determine the sequence of a region of DNA

 

E. All are correct

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

37. The scientist who developed DNA sequencing is:

A. Watson

 

B. Chargaff

 

C. Sanger

 

D. Avery

 

E. Hershey

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

38. Apoptosis is also called:

A. Replication

 

B. Mitosis

 

C. Programmed cell death

 

D. The cell cycle

 

E. Programmed cellular reproduction

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.06.01 Define apoptosis.
SECTION: 08.06
TOPIC: Cell Cycle and Mitosis
 

 

39. Before a cell divides, it must first duplicate its entire:

A. Cytoplasmic contents

 

B. Cell membrane structure

 

C. Array of enzymes

 

D. Genome

 

E. All are correct

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.03.01 Describe how DNA folds into a visible chromosome.
SECTION: 08.03
TOPIC: Cell Cycle and Mitosis
 

 

40. A discreet package of DNA and associated proteins in eukaryotes is a:

A. Chromosome

 

B. Nucleus

 

C. Ribosome

 

D. Golgi body

 

E. Centriole

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.03.01 Describe how DNA folds into a visible chromosome.
SECTION: 08.03
TOPIC: Cell Cycle and Mitosis
 

 

41. A micron is:

A. One tenth (.1) of a meter

 

B. One thousandth (.001) of a meter

 

C. One millionth (.000001) of a meter

 

D. One hundredth (.01) of a meter

 

E. One thousand meters

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.03.01 Describe how DNA folds into a visible chromosome.
SECTION: 08.03
TOPIC: Cell Cycle and Mitosis
 

 

42. A nucleosome consists of:

A. A stretch of DNA and histones

 

B. A stretch of DNA

 

C. An RNA molecule

 

D. A ribosome and RNA

 

E. Histones

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.03.01 Describe how DNA folds into a visible chromosome.
SECTION: 08.03
TOPIC: Cell Cycle and Mitosis
 

 

43. Eukaryotic chromosomes become microscopically visible before cell division because:

A. They become less tightly wound

 

B. They become more tightly wound

 

C. They increase in length

 

D. They become more tightly wound and increase in length

 

E. They become less tightly wound and increase in length

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.03.01 Describe how DNA folds into a visible chromosome.
SECTION: 08.03
TOPIC: Cell Cycle and Mitosis
 

 

44. One of two identical attached copies of a replicated chromosome defines the term:

A. Centromere

 

B. Chromatin

 

C. Chromosome

 

D. Nucleosome

 

E. Chromatid

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.03.01 Describe how DNA folds into a visible chromosome.
SECTION: 08.03
TOPIC: Cell Cycle and Mitosis
 

 

45. A part of a chromosome that attaches sister chromatids to each other defines the term:

A. Chromatin

 

B. Nucleosome

 

C. Centromere

 

D. Histone

 

E. None of the above are correct

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.03.01 Describe how DNA folds into a visible chromosome.
SECTION: 08.03
TOPIC: Cell Cycle and Mitosis
 

 

46. DNA and associated proteins in the nucleus defines the term:

A. Centromere

 

B. Nucleosome

 

C. Histone

 

D. Chromatin

 

E. Chromosome

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.03.01 Describe how DNA folds into a visible chromosome.
SECTION: 08.03
TOPIC: Cell Cycle and Mitosis
 

 

47. A discrete continuous molecule of DNA wrapped around protein defines the term:

A. Nucleosome

 

B. Chromosome

 

C. Centromere

 

D. Histone

 

E. Genome

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.03.01 Describe how DNA folds into a visible chromosome.
SECTION: 08.03
TOPIC: Cell Cycle and Mitosis
 

 

48. “Sister chromatids” are:

A. Genetically identical and attached to each other at centromere

 

B. Genetically different and attached to each other at centromere

 

C. Genetically different

 

D. Genetically identical

 

E. Attached to each other at centromere

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.03.01 Describe how DNA folds into a visible chromosome.
SECTION: 08.03
TOPIC: Cell Cycle and Mitosis
 

 

49. A cell with two full sets of chromosomes would be termed a _______________ cell.

A. Haploid

 

B. Sister

 

C. Somatic

 

D. Diploid

 

E. Germ

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.03.01Describe how DNA folds into a visible chromosome.
SECTION: 08.03
TOPIC: Cell Cycle and Mitosis
 

 

50. A cell with one set of chromosomes would be termed a ________________ cell.

A. Diploid

 

B. Sister

 

C. Somatic

 

D. None of the above are correct

 

E. Haploid

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.03.01 Describe how DNA folds into a visible chromosome.
SECTION: 08.03
TOPIC: Cell Cycle and Mitosis
 

 

51. The pair of unmatched chromosomes in humans:

A. Are the sex chromosomes

 

B. Are the “X” and “Y” chromosomes

 

C. Determine sex (gender) of humans

 

D. Contain different genes

 

E. All are correct

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.03.01 Describe how DNA folds into a visible chromosome.
SECTION: 08.03
TOPIC: Cell Cycle and Mitosis
 

 

52. The process by which a sperm cell combines with an egg cell is:

A. Fertilization

 

B. Recombination

 

C. Replication

 

D. Mitosis

 

E. Germination

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.04.01 Explain what is happening in a cell at each stage of the cell cycle.
SECTION: 08.04
TOPIC: Cell Cycle and Mitosis
 

 

53. If a sperm cell combines with an egg cell the result is a:

A. Diploid cell

 

B. Gamete

 

C. Haploid cell

 

D. Duplicated chromosome

 

E. Gametophyte

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.04.01 Explain what is happening in a cell at each stage of the cell cycle.
SECTION: 08.04
TOPIC: Cell Cycle and Mitosis
 

 

54. An example of a haploid cell is:

A. A skin cell

 

B. A sperm cell

 

C. A zygote

 

D. A stem cell

 

E. All are correct

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.04.01 Explain what is happening in a cell at each stage of the cell cycle.
SECTION: 08.04
TOPIC: Cell Cycle and Mitosis
 

 

55. In humans, specialized cells that produce gametes are:

A. Germ cells

 

B. Somatic cells

 

C. Sperm cells

 

D. Egg cells

 

E. All are correct

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.01.01 Explain the purpose of each step in the human life cycle.
SECTION: 08.01
TOPIC: Cell Cycle and Mitosis
 

 

56. In humans, cells that do not produce gametes are collectively called:

A. Sperm cells

 

B. Egg cells

 

C. Somatic cells

 

D. Germ cells

 

E. All are correct

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.04.01 Explain what is happening in a cell at each stage of the cell cycle.
SECTION: 08.04
TOPIC: Cell Cycle and Mitosis
 

 

57. Mitosis is used for all of the following except:

A. Repair of damaged cells

 

B. Growth of an organism

 

C. Asexual reproduction

 

D. Formation of gametes

 

E. Production of genetically identical daughter cells

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.04.01 Explain what is happening in a cell at each stage of the cell cycle.
SECTION: 08.04
TOPIC: Cell Cycle and Mitosis
 

 

58. Meiosis is a process used for:

A. Repair of damaged cells

 

B. Growth of an organism

 

C. Asexual reproduction

 

D. Production of stem cells

 

E. Production of gametes

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.01.01 Explain the purpose of each step in the human life cycle.
SECTION: 08.01
TOPIC: Cell Cycle and Mitosis
 

 

59. Meiosis is a process used for:

A. Asexual reproduction

 

B. Growth of an organism

 

C. Production of gametes

 

D. Repair of damaged cells

 

E. All are correct

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.01.01 Explain the purpose of each step in the human life cycle.
SECTION: 08.01
TOPIC: Cell Cycle and Mitosis
 

 

60. Immature cells that retain the potential to develop into multiple cell types are:

A. Germ cells

 

B. Somatic cells

 

C. Stem cells

 

D. Nerve cells

 

E. All are correct

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.01.01 Explain the purpose of each step in the human life cycle.
SECTION: 08.01
TOPIC: Cell Cycle and Mitosis
 

 

61. The two main stages of the cell cycle are:

A. Interphase and cytokinesis

 

B. Interphase and mitosis

 

C. Mitosis and cytokinesis

 

D. Interphase and prophase

 

E. Mitosis and meiosis

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.04.01 Explain what is happening in a cell at each stage of the cell cycle.
SECTION: 08.04
TOPIC: Cell Cycle and Mitosis
 

 

62. The splitting of a cell into two daughter cells in the cell cycle is:

A. Mitosis

 

B. Interphase

 

C. Cytokinesis

 

D. Metaphase

 

E. Anaphase

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.04.01 Explain what is happening in a cell at each stage of the cell cycle.
SECTION: 08.04
TOPIC: Cell Cycle and Mitosis
 

 

63. The division of the nucleus during the cell cycle is:

A. Mitosis

 

B. Interphase

 

C. Synthesis

 

D. Cytokinesis

 

E. Replication

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.04.01 Explain what is happening in a cell at each stage of the cell cycle.
SECTION: 08.04
TOPIC: Cell Cycle and Mitosis
 

 

64. The replication of DNA during the cell cycle occurs during:

A. Mitosis

 

B. Cytokinesis

 

C. Prophase

 

D. Telophase

 

E. Interphase

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.04.01 Explain what is happening in a cell at each stage of the cell cycle.
SECTION: 08.04
TOPIC: Cell Cycle and Mitosis
 

 

65. The correct sequence for the phases of the cell cycle is:

A. Interphase – prophase – prometaphase – metaphase – anaphase – telophase

 

B. Prophase – prometaphase – metaphase – anaphase – telophase

 

C. Prophase – prometaphase – anaphase – metaphase – telophase

 

D. Interphase – prometaphase – prophase – metaphase – anaphase – telophase

 

E. Metaphase – anaphase – interphase – prophase – telophase

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.04.01 Explain what is happening in a cell at each stage of the cell cycle.
SECTION: 08.04
TOPIC: Cell Cycle and Mitosis
 

 

66. The correct sequence for the phases of mitosis is:

A. Prometaphase – prophase – metaphase – anaphase – telophase

 

B. Interphase – prophase – metaphase – anaphase – telophase

 

C. Interphase – metaphase – anaphase – prophase – telophase

 

D. Prophase – metaphase – prometaphase – anaphase – telophase

 

E. Prophase – prometaphase – metaphase – anaphase – telophase

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.04.02 Diagram and identify the phases in mitosis.
SECTION: 08.04
TOPIC: Cell Cycle and Mitosis
 

 

67. The portion of the cytoskeleton that enables the chromosomes to be separated equally into two sets is the:

A. Golgi body

 

B. Centromere

 

C. Centrosome

 

D. Mitotic spindle

 

E. Kinetochore

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.04.02 Diagram and identify the phases in mitosis.
SECTION: 08.04
TOPIC: Cell Cycle and Mitosis
 

 

68. The structure that organizes the protein subunits of the mitotic spindle is the:

A. Centromere

 

B. Kinetochore

 

C. Centrosome

 

D. Cytoskeleton

 

E. Microfilaments

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.04.02 Diagram and identify the phases in mitosis.
SECTION: 08.04
TOPIC: Cell Cycle and Mitosis
 

 

69. The proteins that attach chromosomes to the mitotic spindle are:

A. Kinetochores

 

B. Chromatids

 

C. Nucleosomes

 

D. Centromeres

 

E. Histones

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.04.02 Diagram and identify the phases in mitosis.
SECTION: 08.04
TOPIC: Cell Cycle and Mitosis
 

 

70. The phase of mitosis in which the nuclear envelope breaks into small pieces is:

A. Prophase

 

B. Metaphase

 

C. Anaphase

 

D. Prometaphase

 

E. Telophase

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.04.02 Diagram and identify the phases in mitosis.
SECTION: 08.04
TOPIC: Cell Cycle and Mitosis
 

 

71. The phase of mitosis in which the centromeres split and sister chromatids are pulled to opposite poles of the cell is:

A. Prophase

 

B. Anaphase

 

C. Prometaphase

 

D. Metaphase

 

E. Telophase

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.04.02 Diagram and identify the phases in mitosis.
SECTION: 08.04
TOPIC: Cell Cycle and Mitosis
 

 

72. The phase of mitosis in which the chromosomes are aligned along the equator of the cell is:

A. Metaphase

 

B. Prophase

 

C. Prometaphase

 

D. Anaphase

 

E. Telophase

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.04.02 Diagram and identify the phases in mitosis.
SECTION: 08.04
TOPIC: Cell Cycle and Mitosis
 

 

73. The phase of mitosis in which the nuclear envelope reforms is:

A. Prophase

 

B. Prometaphase

 

C. Metaphase

 

D. Anaphase

 

E. Telophase

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.04.02 Diagram and identify the phases in mitosis.
SECTION: 08.04
TOPIC: Cell Cycle and Mitosis
 

 

74. The phase of mitosis in which the chromosomes condense and centrosomes move to opposite poles of the cell is:

A. Prometaphase

 

B. Metaphase

 

C. Prophase

 

D. Anaphase

 

E. Telophase

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.04.02 Diagram and identify the phases in mitosis.
SECTION: 08.04
TOPIC: Cell Cycle and Mitosis
 

 

75. The first sign of cytokinesis in an animal cell is the formation of a:

A. Cell plate

 

B. Cleavage furrow

 

C. Cell wall

 

D. Nucleolus

 

E. Nuclear envelope

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.04.02 Diagram and identify the phases in mitosis.
SECTION: 08.04
TOPIC: Cell Cycle and Mitosis
 

 

76. The first sign of cytokinesis in a plant cell is the formation of a:

A. Nuclear envelope

 

B. Nucleolus

 

C. Cleavage furrow

 

D. Cell plate

 

E. Spindle fiber

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.04.02 Diagram and identify the phases in mitosis.
SECTION: 08.04
TOPIC: Cell Cycle and Mitosis
 

 

77. If scientists could inactivate telomerase in specific cells, the primary reason for this would most likely be the stopping of:

A. Aerobic respiration

 

B. Meiosis

 

C. Aging of cells

 

D. The formation of cancer

 

E. All are correct

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.04.02 Diagram and identify the phases in mitosis.
SECTION: 08.04
TOPIC: Cell Cycle and Mitosis
 

 

78. If scientists could increase telomerase production in specific cells, the primary reason for this would most likely be the stopping of:

A. Aging of cells

 

B. Aerobic respiration

 

C. Meiosis

 

D. Cancer cell formation

 

E. All are correct

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.04.02 Diagram and identify the phases in mitosis.
SECTION: 08.04
TOPIC: Cell Cycle and Mitosis
 

 

79. In an asexual life cycle, cells reproduce by:

A. Meiosis

 

B. Fertilization

 

C. Meiosis and Fertilization

 

D. Mitosis

 

E. All are correct

 

BLOOM’S LEVEL: 2. Understand
LEARNING OUTCOME: 08.01.01 Explain the purpose of each step in the human life cycle.
SECTION: 08.01
TOPIC: DNA Replication
 

 

80. In a sexual life cycle, a zygote grows to an adult by:

A. Meiosis

 

B. Fertilization

 

C. Meiosis and Fertilization

 

D. Mitosis

 

E. All are correct

 

BLOOM’S LEVEL: 2. Understand
LEARNING OUTCOME: 08.01.01 Explain the purpose of each step in the human life cycle.
SECTION: 08.01
TOPIC: DNA Replication
 

 

81. How does the space between our fingers arise?

A. The cells die by necrosis

 

B. Mitosis of the cells is blocked

 

C. The cells die by apoptosis

 

D. Meiosis of the cells is blocked

 

E. The cells become part of the fingers

 

BLOOM’S LEVEL: 2. Understand
LEARNING OUTCOME: 08.01.01 Explain the purpose of each step in the human life cycle.
SECTION: 08.01
TOPIC: DNA Replication
 

 

82. If one strand of a DNA molecule has the base sequence of 5′ ATGTGCC 3′ the complementary strand of DNA will read:

A. 3′ ATGTGCC 5′

 

B. 3′ TACACGG 5′

 

C. 3′ UACACGG 5′

 

D. 3′ CGTGTAA 5′

 

E. 3′ GGCACAT 5′

 

BLOOM’S LEVEL: 3. Apply
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

83. If one strand of a DNA molecule has the base sequence of 5′ CGGCATTA 3′ the complementary strand of DNA will read:

A. 3′ CGGCATTA 5′

 

B. 3′ ATTACGGC 5′

 

C. 3′ GCCGTUUT 5′

 

D. 3′ GCCGTAAT 5′

 

E. 3′ TAATGCCG 5′

 

BLOOM’S LEVEL: 3. Apply
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

84. If a mutation causes the “T” base in the base sequence 5′ AGTCCG 3′ to be read as a “G” base, DNA replication of the mutated sequence will read:

A. 3′ TCCGGC 5′

 

B. 3′ AGGCCG 5′

 

C. 3′ CTTAAT 5′

 

D. 3′ UCCGGC 5′

 

E. 3′ AGTCCG 5′

 

BLOOM’S LEVEL: 4. Analyze
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

85. If a mutation causes the “G” base in the base sequence 5′ AATGAC 3′ to be read as a “T” base, DNA replication of the mutated sequence will read:

A. 3′ AATTAC 5′

 

B. 3′ TTCCTG 5′

 

C. 3′ GGCCGT 5′

 

D. 3′ TTAATG 5′

 

E. 3′ AATGAC 5′

 

BLOOM’S LEVEL: 4. Analyze
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

86. Why does a replication fork have a leading and lagging strand?

A. Because DNA synthesis always goes from 3′ to 5′

 

B. Because DNA synthesis can grow off of either the 3′ or 5′ end

 

C. Because DNA synthesis always goes from 5′ to 3′

 

D. To slow down DNA synthesis to make time for mitosis

 

E. To slow down DNA synthesis to make time for the production of primers

 

BLOOM’S LEVEL: 2. Understand
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

87. When DNA replicates:

A. The original DNA is not affected and a new double-stranded DNA is made from two new strands of DNA

 

B. One strand of the original DNA ends up in each of the new DNA molecules

 

C. The original DNA unwinds, and multiple copies of a region are transcribed before the DNA closes back up

 

D. Transcription factors determine where to begin DNA replication

 

E. A cell that was diploid (2N) will now be tetraploid (4N)

 

BLOOM’S LEVEL: 2. Understand
LEARNING OUTCOME: 08.02.02 Explain what features of DNA allow semiconservative replication to occur.
SECTION: 08.02
TOPIC: DNA Replication
 

 

88. Based on the structure of the DNA backbone you would predict the surface of histones to be:

A. Negatively charged

 

B. Positively charged

 

C. Neutral

 

D. Hydrophobic

 

E. Hydrophilic

 

BLOOM’S LEVEL: 3. Apply
LEARNING OUTCOME: 08.03.01 Describe how DNA folds into a visible chromosome.
SECTION: 08.03
TOPIC: DNA Replication
 

 

89. A cell would pack its DNA as chromatin in preparation for:

A. Replication

 

B. Transcription

 

C. Translation

 

D. Splicing

 

E. Mitosis

 

BLOOM’S LEVEL: 3. Apply
LEARNING OUTCOME: 08.03.01 Describe how DNA folds into a visible chromosome.
SECTION: 08.03
TOPIC: Cell Cycle and Mitosis
 

 

90. The chemotherapy drug taxol inhibits microtubule function. A cell treated with taxol would become stuck in which phase?

A. Prophase

 

B. Metaphase

 

C. Anaphase

 

D. Telophase

 

E. Cytokinesis

 

BLOOM’S LEVEL: 3. Apply
LEARNING OUTCOME: 08.04.01 Explain what is happening in a cell at each stage of the cell cycle.
SECTION: 08.04
TOPIC: Cell Cycle and Mitosis
 

 

91. Why don’t plant cells form a cleavage furrow during cytokinesis?

A. Because they don’t have a cell membrane

 

B. Because their cells don’t divide after mitosis, but become one larger cell with multiple nuclei

 

C. Because they have a cell wall

 

D. Because they don’t have a nucleus

 

E. All are correct

 

BLOOM’S LEVEL: 3. Apply
LEARNING OUTCOME: 08.04.01 Explain what is happening in a cell at each stage of the cell cycle.
SECTION: 08.04
TOPIC: Cell Cycle and Mitosis
 

 

92. By ignoring a checkpoint in the cell cycle, a cancer cell may:

A. Divide after mutations are fixed

 

B. Divide before its DNA is completely replicated

 

C. Condense its chromosomes before mitosis

 

D. Align chromosomes on the equator of the cell during metaphase

 

E. Pull chromosomes apart during anaphase

 

BLOOM’S LEVEL: 3. Apply
LEARNING OUTCOME: 08.05.01 Explain what is meant by a checkpoint and how these relate to cancer.
SECTION: 08.05
TOPIC: Cell Cycle and Mitosis
 

 

93. In order for a cell to become cancerous, oncogenes must be ___ and tumor suppressors ___.

A. Inactivated, activated

 

B. Both activated

 

C. Both inactivated

 

D. Activated, inactivated

 

BLOOM’S LEVEL: 2. Understand
LEARNING OUTCOME: 08.05.02 Compare and contrast the role of an oncogene and tumor suppressor in cancer.
SECTION: 08.05
TOPIC: Cell Cycle and Mitosis
 

 

94. The enzyme telomerase adds DNA to the ends of chromosomes. Why would cancer cells express high levels of telomerase?

A. As telomeres get shorter a cell loses the ability to divide

 

B. The longer a chromosome is, the more genes a cancer cell will have

 

C. Longer chromosomes have more active genes

 

D. To allow the chromosomes to be replicated more rapidly

 

E. Telomerase is a tumor suppressor

 

BLOOM’S LEVEL: 3. Apply
LEARNING OUTCOME: 08.05.02 Compare and contrast the role of an oncogene and tumor suppressor in cancer.
SECTION: 08.05
TOPIC: Cell Cycle and Mitosis
 

 

95. Stem cells from a blastocyst

A. Can only produce certain types of cells

 

B. Can form any type of cell in the body

 

C. Cannot survive outside of the blastocyst

 

D. Cannot be formed by in vitro fertilization

 

E. Can be obtained from adult tissues

 

BLOOM’S LEVEL: 2. Understand
LEARNING OUTCOME: 08.07.01 Compare and contrast the growth of a normal cell and a stem cell.
SECTION: 08.07
TOPIC: Cell Cycle and Mitosis
 

 

96. Stem cells from an adult

A. Can only produce certain types of cells

 

B. Can form any type of cell in the body

 

C. Cannot survive outside of the adult

 

D. Can be formed by in vitro fertilization

 

E. Are obtained from a blastocyst

 

BLOOM’S LEVEL: 2. Understand
LEARNING OUTCOME: 08.07.01 Compare and contrast the growth of a normal cell and a stem cell.
SECTION: 08.07
TOPIC: Cell Cycle and Mitosis
 

 

97. In cloning the sheep Dolly, a nucleus was implanted into an egg that had its nucleus removed. The result of this somatic cell transfer was a ____ egg.

A. Haploid

 

B. Fertilized

 

C. Embryonic

 

D. Diploid

 

E. Tetraploid

 

BLOOM’S LEVEL: 3. Apply
LEARNING OUTCOME: 08.07.02 Identify the advantages and risks of cloning a mammal.
SECTION: 08.07
TOPIC: Cell Cycle and Mitosis
 

 

98. For the polymerase chain reaction (PCR) to work, the Taq _______ must be heat stable to avoid denaturation.

A. DNA polymerase

 

B. RNA polymerase

 

C. Ribosome

 

D. Primase

 

E. DNA

 

LEARNING OUTCOME: 08.07.02 Identify the advantages and risks of cloning a mammal.
SECTION: 08.07
TOPIC: Cell Cycle and Mitosis
 

 

99. Why would a cancer cell need to induce angiogenesis?

A. Because cells in the center of a tumor become too far from blood vessels

 

B. It is the first step in metastasis

 

C. To avoid checkpoints in the cell cycle

 

D. It would activate oncogenes

 

E. It would inactivate tumor suppressors

 

BLOOM’S LEVEL: 3. Apply
LEARNING OUTCOME: 08.05.01 Explain what is meant by a checkpoint and how these relate to cancer.
SECTION: 08.05
TOPIC: Cell Cycle and Mitosis
TOPIC: Investigating Life
 

 

100. Cancer cells secrete molecules that stimulate endothelial cells to divide by first:

A. Passing through the S phase checkpoint

 

B. Lining chromosomes up on the equator of the cell

 

C. Pulling chromosomes apart toward the poles of the cell

 

D. Passing through the G1 checkpoint

 

E. Passing through the G2 checkpoint

 

BLOOM’S LEVEL: 3. Apply
LEARNING OUTCOME: 08.05.01 Explain what is meant by a checkpoint and how these relate to cancer.
SECTION: 08.05
TOPIC: Cell Cycle and Mitosis
TOPIC: Investigating Life
 

 

101. Why did the researchers induce cancer in mice by injecting cancer cells, instead of just doing the experiment on isolated cancer cells in culture?

A. Cancer cells can go through angiogenesis in culture

 

B. Cancer cells cannot be grown outside of the body in culture

 

C. Angiogenesis occurs in a whole organism

 

D. Tumor suppressors are only active in whole tumors

 

E. Oncogenes are only active in whole tumors

 

BLOOM’S LEVEL: 3. Apply
LEARNING OUTCOME: 08.05.01 Explain what is meant by a checkpoint and how these relate to cancer.
SECTION: 08.05
TOPIC: Cell Cycle and Mitosis
TOPIC: Investigating Life
 

 

102. Cyclophosphamide forms crosslinks between the two strands of DNA in a chromosome. How would this be effective in chemotherapy?

A. It would block splicing

 

B. It would block DNA replication

 

C. It would activate oncogenes

 

D. It would inactivate tumor suppressors

 

E. It would block metaphase

 

BLOOM’S LEVEL: 3. Apply
LEARNING OUTCOME: 08.05.01 Explain what is meant by a checkpoint and how these relate to cancer.
SECTION: 08.05
TOPIC: Cell Cycle and Mitosis
TOPIC: Investigating Life
 

 

103. What hypothesis were the researchers testing by treating tumors with endostatin and cyclophosphamide?

A. Because endostatin works on endothelial cells, natural selection for resistance will not occur in tumor cells

 

B. Because endostatin works on tumor cells, natural selection for resistance will not occur in endothelial cells

 

C. Because cyclophosphamide works on endothelial cells, natural selection for resistance will not occur in tumor cells

 

D. Because cyclophosphamide works on tumor cells, natural selection for resistance will not occur in endothelial cells

 

BLOOM’S LEVEL: 4. Analyze
LEARNING OUTCOME: 08.05.01 Explain what is meant by a checkpoint and how these relate to cancer.
SECTION: 08.05
TOPIC: Cell Cycle and Mitosis
TOPIC: Investigating Life
 

 

   

 

104. What is the dependent variable in figure 8.26?

A. The volume of the tumor in humans

 

B. Treatment days

 

C. Treatment with endostatin

 

D. Treatment with cyclophosphamide

 

E. The volume of the tumor in mice

 

BLOOM’S LEVEL: 4. Analyze
LEARNING OUTCOME: 01.03.01 Identify standardized, dependent, and independent variables in an experiment.
LEARNING OUTCOME: 08.05.01 Explain what is meant by a checkpoint and how these relate to cancer.
SECTION: 01.03
SECTION: 08.05
TOPIC: Cell Cycle and Mitosis
TOPIC: Investigating Life
 

 

105. What did the researchers conclude from figure 8.26a?

A. Endostatin shrunk tumors but resistance developed

 

B. Cyclophosphamide delayed the growth of tumors without development of resistance

 

C. Endostatin shrunk tumors without development of resistance

 

D. Cyclophosphamide delayed the growth of tumors but resistance developed

 

E. Tumors in untreated cells shrank in size

 

BLOOM’S LEVEL: 4. Analyze
LEARNING OUTCOME: 01.03.01 Identify standardized, dependent, and independent variables in an experiment.
LEARNING OUTCOME: 08.05.01 Explain what is meant by a checkpoint and how these relate to cancer.
SECTION: 01.03
SECTION: 08.05
TOPIC: Cell Cycle and Mitosis
TOPIC: Investigating Life
 

 

106. What did the researchers conclude from figure 8.26b?

A. Cyclophosphamide delayed the growth of tumors but resistance developed

 

B. Endostatin shrunk tumors without development of resistance

 

C. Endostatin shrunk tumors but resistance developed

 

D. Cyclophosphamide delayed the growth of tumors without development of resistance

 

E. Tumors in untreated cells shrank in size

 

BLOOM’S LEVEL: 4. Analyze
LEARNING OUTCOME: 01.03.01 Identify standardized, dependent, and independent variables in an experiment.
LEARNING OUTCOME: 08.05.01 Explain what is meant by a checkpoint and how these relate to cancer.
SECTION: 01.03
SECTION: 08.05
TOPIC: Cell Cycle and Mitosis
TOPIC: Investigating Life
 

 

107. Endostatin is a 184-amino acid protein. How could enough endostatin be produced to use as a drug?

A. The endostatin gene would be cloned and injected into a patient to produce endostatin

 

B. Endostatin protein would be injected into bacteria to produce more endostatin

 

C. The endostatin gene would be cloned and injected into bacteria to produce endostatin

 

D. Inject endostatin mRNA into a patient to produce endostatin

 

E. Inject endostatin antisense RNA into a bacteria to produce endostatin

 

BLOOM’S LEVEL: 3. Apply
LEARNING OUTCOME: 07.09.01 Outline the steps required to make a transgenic organism.
LEARNING OUTCOME: 08.05.01 Explain what is meant by a checkpoint and how these relate to cancer.
SECTION: 07.09
SECTION: 08.05
TOPIC: Cell Cycle and Mitosis
TOPIC: Investigating Life
TOPIC: Molecular Biology
 

 

108. Endostatin is a 184-amino acid protein that only affects endothelial cells. What is the best explanation for this observation?

A. Endothelial cells produce endostatin

 

B. Endostatin can diffuse across the membrane of endothelial cells

 

C. Only endothelial cells are exposed to endostatin

 

D. Endothelial cells have a receptor on their cell membrane for endostatin

 

E. Endostatin enters endothelial cells by endocytosis

 

BLOOM’S LEVEL: 3. Apply
LEARNING OUTCOME: 03.03.02 Identify different functions of membrane proteins.
LEARNING OUTCOME: 08.05.01 Explain what is meant by a checkpoint and how these relate to cancer.
SECTION: 03.03
SECTION: 08.05
TOPIC: Cell Cycle and Mitosis
TOPIC: Cell Structure
TOPIC: Investigating Life
 

 

True / False Questions

109. A bacteriophage infects a bacterial cell by injecting nucleic acid into the bacterium.

TRUE

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.00.01 Explain how cells divide to give rise to identical cells.
SECTION: 08.01
TOPIC: DNA Replication
 

 

110. Variants or alternate forms of a gene are called alleles:

TRUE

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

111. Any change in a cell’s DNA sequence is a mutation.

TRUE

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

112. Change in a cell’s DNA sequence is a regular occurrence in the process of replication.

FALSE

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

113. Each newly replicated molecule of DNA contains one conserved strand from the original DNA molecule.

TRUE

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

114. The process used to determine the order of bases in DNA is polymerase chain reaction.

FALSE

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

115. The process used to determine the order of bases in DNA is DNA sequencing.

TRUE

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

116. The process used to rapidly produce DNA sequences of interest is polymerase chain reaction.

TRUE

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

117. The process used to rapidly produce DNA sequences of interest is DNA sequencing.

FALSE

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step.
SECTION: 08.02
TOPIC: DNA Replication
 

 

118. A replicated chromosome consists of two “sister chromatids.”

TRUE

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.03.01 Describe how DNA folds into a visible chromosome.
SECTION: 08.03
TOPIC: DNA Replication
 

 

119. Replication takes place during the G1 phase of interphase.

FALSE

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.04.01 Explain what is happening in a cell at each stage of the cell cycle.
SECTION: 08.04
TOPIC: DNA Replication
 

 

120. During cytokinesis of a plant cell, the cell divides by forming a cleavage furrow.

FALSE

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.04.01 Explain what is happening in a cell at each stage of the cell cycle.
SECTION: 08.04
TOPIC: DNA Replication
 

 

121. During the cell cycle there are several checkpoints that ensure that the cell cycle is proceeding correctly.

TRUE

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.05.01 Explain what is meant by a checkpoint and how these relate to cancer.
SECTION: 08.05
TOPIC: DNA Replication
 

 

122. Cells that produce telomerase can usually divide many more times than cells that do not produce telomerase.

TRUE

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.05.02 Compare and contrast the role of an oncogene and tumor suppressor in cancer.
SECTION: 08.05
TOPIC: DNA Replication
 

 

123. If scientists could stimulate telomerase production in cancer cells, this would most likely help stop the cancerous growth.

FALSE

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.05.02 Compare and contrast the role of an oncogene and tumor suppressor in cancer.
SECTION: 08.05
TOPIC: DNA Replication
 

 

124. An abnormal mass of tissue is a tumor.

TRUE

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.05.02 Compare and contrast the role of an oncogene and tumor suppressor in cancer.
SECTION: 08.05
TOPIC: DNA Replication
 

 

125. If a cancer metastasizes, its cells travel through the blood stream and colonize other areas of the body.

TRUE

 

BLOOM’S LEVEL: 1. Remember
LEARNING OUTCOME: 08.05.02 Compare and contrast the role of an oncogene and tumor suppressor in cancer.
SECTION: 08.05
TOPIC: DNA Replication
 

 

 

Chapter 008 – DNA Replication, Mitosis and the Cell Cycle Summary

Category # of Questions
BLOOM’S LEVEL: 1. Remember 95
BLOOM’S LEVEL: 2. Understand 8
BLOOM’S LEVEL: 3. Apply 15
BLOOM’S LEVEL: 4. Analyze 6
LEARNING OUTCOME: 01.03.01 Identify standardized, dependent, and independent variables in an experiment. 3
LEARNING OUTCOME: 03.03.02 Identify different functions of membrane proteins. 1
LEARNING OUTCOME: 07.09.01 Outline the steps required to make a transgenic organism. 1
LEARNING OUTCOME: 08.00.01 Explain how cells divide to give rise to identical cells. 8
LEARNING OUTCOME: 08.01.01 Explain the purpose of each step in the human life cycle. 7
LEARNING OUTCOME: 08.02.01 Describe the steps of replication and the function of enzymes in each step. 41
LEARNING OUTCOME: 08.02.02 Explain what features of DNA allow semiconservative replication to occur. 3
LEARNING OUTCOME: 08.03.01 Describe how DNA folds into a visible chromosome. 15
LEARNING OUTCOME: 08.03.01Describe how DNA folds into a visible chromosome. 1
LEARNING OUTCOME: 08.04.01 Explain what is happening in a cell at each stage of the cell cycle. 14
LEARNING OUTCOME: 08.04.02 Diagram and identify the phases in mitosis. 13
LEARNING OUTCOME: 08.05.01 Explain what is meant by a checkpoint and how these relate to cancer. 12
LEARNING OUTCOME: 08.05.02 Compare and contrast the role of an oncogene and tumor suppressor in cancer. 6
LEARNING OUTCOME: 08.06.01 Define apoptosis. 1
LEARNING OUTCOME: 08.07.01 Compare and contrast the growth of a normal cell and a stem cell. 2
LEARNING OUTCOME: 08.07.02 Identify the advantages and risks of cloning a mammal. 2
SECTION: 01.03 3
SECTION: 03.03 1
SECTION: 07.09 1
SECTION: 08.01 15
SECTION: 08.02 44
SECTION: 08.03 16
SECTION: 08.04 27
SECTION: 08.05 18
SECTION: 08.06 1
SECTION: 08.07 4
TOPIC: Cell Cycle and Mitosis 61
TOPIC: Cell Structure 1
TOPIC: DNA Replication 64
TOPIC: Investigating Life 10
TOPIC: Molecular Biology 1

 

 

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