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Prescotts Microbiology 10th Edition Willey Sherwood Woolverton Test Bank

ISBN-13: 978-1259281594

ISBN-10: 1259281590

 

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Prescotts Microbiology 10th Edition Willey Sherwood Woolverton Test Bank

ISBN-13: 978-1259281594

ISBN-10: 1259281590

 

 

 

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Chapter 38

Human Diseases Caused by Viruses and Prions

 

 

Multiple Choice Questions

  1. In influenza virus, antigenic shift
    A.results from reassortment of genomes when two different strains of flu viruses infect the same cell.
    B. results from the accumulation of mutations in HA and NA in a single strain of flu virus.
    C. can result in major epidemics or pandemics.
    D. results from reassortment of genomes when two different strains of flu viruses infect the same cell and can result in major epidemics or pandemics.

 

ASM Objective: 04.01 Genetic variations can impact microbial functions (e.g., in biofilm formation, pathogenicity and drug resistance).
ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 04 Information Flow and Genetics
ASM Topic: Module 05 Microbial Systems
Blooms Level: 2. Understand
Learning Outcome: 38.01.01 Report the common viral diseases spread by airborne transmission
Learning Outcome: 38.01.03 Correlate airborne viral infection and disease severity with viral virulence factors
Learning Outcome: 38.03.02 Identify typical signs and symptoms of common viral diseases spread by direct contact
Section: 38.01
Section: 38.03
Topic: Respiratory System Infections
Topic: Viral Infections
Topic: Viruses

 

  1. The rash associated with German measles is most likely caused by
    A.the virus infecting the cells of the skin.
    B. the virus infecting the cells of the dermal layer beneath the skin.
    C. an immunological reaction to the virus.
    D.  All of the choices are correct.

 

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 2. Understand
Learning Outcome: 38.01.02 Identify typical signs and symptoms of viral diseases spread by airborne transmission
Learning Outcome: 38.01.03 Correlate airborne viral infection and disease severity with viral virulence factors
Section: 38.01
Topic: Skin/Skeletal Infections
Topic: Viruses

 

True / False Questions

  1. Antigenic variation is common in influenza B and C but is rare in influenza A.
    FALSE

 

ASM Objective: 04.01 Genetic variations can impact microbial functions (e.g., in biofilm formation, pathogenicity and drug resistance).
ASM Topic: Module 04 Information Flow and Genetics
Blooms Level: 2. Understand
Learning Outcome: 38.01.03 Correlate airborne viral infection and disease severity with viral virulence factors
Section: 38.01
Topic: Respiratory System Infections
Topic: Viral Infections
Topic: Viruses

 

Multiple Choice Questions
 

  1. Chickenpox is caused by the __________ virus.
    A.rubella
    B. rubeola
    C. coxsackievirus B
    D. varicella

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 1. Remember
Learning Outcome: 38.01.01 Report the common viral diseases spread by airborne transmission
Section: 38.01
Topic: Skin/Skeletal Infections
Topic: Viral Infections
Topic: Viruses

  1. The reactivated form of chickenpox is called _________.
    A. rubella
    B.  adenovirus
    C.  herpes zoster
    D.  rubeola

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 1. Remember
Learning Outcome: 38.01.02 Identify typical signs and symptoms of viral diseases spread by airborne transmission
Section: 38.01
Topic: Nervous System Infections
Topic: Skin/Skeletal Infections
Topic: Viral Infections
Topic: Viruses

 

  1. German measles is caused by the __________ virus.
    A.rubella
    B. herpes-zoster
    C. reovirus
    D. coxsackievirus A

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 1. Remember
Learning Outcome: 38.01.01 Report the common viral diseases spread by airborne transmission
Section: 38.01
Topic: Skin/Skeletal Infections
Topic: Viral Infections
Topic: Viruses

  1. Women of childbearing age should be vaccinated against _________.
    A. chickenpox
    B.  German measles
    C.  shingles
    D.  influenza A

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 1. Remember
Learning Outcome: 38.01.01 Report the common viral diseases spread by airborne transmission
Learning Outcome: 38.01.02 Identify typical signs and symptoms of viral diseases spread by airborne transmission
Section: 38.01
Topic: Skin/Skeletal Infections
Topic: Viruses

 

  1. Congenital rubella syndrome usually occurs in the time frame of the
    A.first trimester of pregnancy.
    B. second trimester of pregnancy.
    C. third trimester of pregnancy.
    D. entire pregnancy.

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 2. Understand
Learning Outcome: 38.01.02 Identify typical signs and symptoms of viral diseases spread by airborne transmission
Section: 38.01
Topic: Skin/Skeletal Infections
Topic: Viral Infections
Topic: Viruses

  1. With respect to orthomyxoviruses, changes in antigenicity usually occur as a result of
    A.antigenic drift.
    B. antigenic shift.
    C. frameshift mutations.
    D.  both antigenic drift and antigenic shift.
  2. both antigenic drift and frameshift mutations.
  3. both antigenic shift and frameshift mutations.

 

 

ASM Objective: 04.01 Genetic variations can impact microbial functions (e.g., in biofilm formation, pathogenicity and drug resistance).
ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 04 Information Flow and Genetics
ASM Topic: Module 05 Microbial Systems
Blooms Level: 2. Understand
Learning Outcome: 38.01.03 Correlate airborne viral infection and disease severity with viral virulence factors
Section: 38.01
Topic: Respiratory System Infections
Topic: Viral Infections
Topic: Viruses

 

  1. Antigenic variation occurs almost yearly with the influenza _________ virus.
    A.A
    B. B
    C. C
    D. D

 

ASM Objective: 04.01 Genetic variations can impact microbial functions (e.g., in biofilm formation, pathogenicity and drug resistance).
ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 04 Information Flow and Genetics
ASM Topic: Module 05 Microbial Systems
Blooms Level: 2. Understand
Learning Outcome: 38.01.03 Correlate airborne viral infection and disease severity with viral virulence factors
Section: 38.01
Topic: Respiratory System Infections
Topic: Viral Infections
Topic: Viruses

  1. Which of the following drugs has been shown to reduce the duration and symptoms of influenza?
    A.Penicillin
  2. AZT
    C.Oseltamivir
  3. Acyclovir

 

 

ASM Objective: 03.04 The growth of microorganisms can be controlled by physical, chemical, mechanical, or biological methods.
ASM Topic: Module 03 Metabolic Pathways
Blooms Level: 2. Understand
Learning Outcome: 38.01.02 Identify typical signs and symptoms of viral diseases spread by airborne transmission
Section: 38.01
Topic: Antivirals
Topic: Respiratory System Infections
Topic: Viral Infections
Topic: Viruses

 

  1. Mumps is caused by a _________.
    A. morbillis virus
    B.  paramyxovirus
    C.  adenovirus
    D.  synctial virus

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 1. Remember
Learning Outcome: 38.01.01 Report the common viral diseases spread by airborne transmission
Learning Outcome: 38.01.02 Identify typical signs and symptoms of viral diseases spread by airborne transmission
Section: 38.01
Topic: Viral Infections
Topic: Viruses

  1. Acute respiratory viruses cause _________.
    A. rhinitis
    B.  tonsillitis
    C.  bronchitis
    D.  All of the choices are correct.

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 1. Remember
Learning Outcome: 38.01.01 Report the common viral diseases spread by airborne transmission
Section: 38.01
Topic: Respiratory System Infections
Topic: Viral Infections
Topic: Viruses

 

  1. In those cases of pneumonia for which no cause is determined by laboratory findings, __________ pneumonia can be assumed if __________ pneumonia has been ruled out.
    A. viral; mycoplasmal
    B.  bacterial; viral
    C.  mycoplasmal; viral
    D.  mycoplasmal; bacterial

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 1. Remember
Learning Outcome: 38.01.01 Report the common viral diseases spread by airborne transmission
Section: 38.01
Topic: Respiratory System Infections
Topic: Viral Infections
Topic: Viruses

  1. Which of the following did not play a role in the eradication of smallpox?
    A. Ease of diagnosis by readily recognized clinical features
    B.  No known reservoir outside of human hosts
    C.  A short period of infectivity
    D.  The availability of effective antiviral agents that block replication
    E.  All of these characteristics played a role in the eradication of smallpox

 

ASM Objective: 03.04 The growth of microorganisms can be controlled by physical, chemical, mechanical, or biological methods.
ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 03 Metabolic Pathways
ASM Topic: Module 05 Microbial Systems
Blooms Level: 3. Apply
Learning Outcome: 38.01.01 Report the common viral diseases spread by airborne transmission
Section: 38.01
Topic: Skin/Skeletal Infections
Topic: Viral Infections
Topic: Viruses

 

  1. Koplik’s spots are small red lesions with a white center that form in the mouth and are associated with _________.
    A. mumps
    B.  measles
    C.  chickenpox
    D.  flavivirus infection

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 1. Remember
Learning Outcome: 38.01.02 Identify typical signs and symptoms of viral diseases spread by airborne transmission
Section: 38.01
Topic: Viral Infections
Topic: Viruses

  1. Which of the following syndromes may result from infection by an arthropod-borne virus?
    A. Fevers of undifferentiated type with or without a rash
  2. Encephalitis, often with a high fatality rate
  3. Hemorrhagic fevers
  4. All of the choices are correct.

 

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 2. Understand
Learning Outcome: 38.02.01 Report the two common arthropod-borne viral diseases
Section: 38.02
Topic: Arthropod Vectors
Topic: Nervous System Infections
Topic: Viral Infections
Topic: Viruses

 

  1. West Nile virus has been detected in _________ states of the United.States.
    A. 25
    B.  50
    C.  47
    D.  10

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 1. Remember
Learning Outcome: 38.02.03 Correlate arthropod-borne virus infection with geography and time of year
Section: 38.02
Topic: Arthropod Vectors
Topic: Nervous System Infections
Topic: Viral Infections
Topic: Viruses

  1. Diagnosis of West Nile virus infection is through detection of
    A.viral growth in cell cultures.
    B.  a rise in neutralizing antibody in a patient’s serum.
  2. PCR analysis from saliva samples.
    D.culture on artificial media.

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 2. Understand
Learning Outcome: 38.02.02 Identify typical signs and symptoms of two arthropod-borne viral diseases
Section: 38.02
Topic: Nervous System Infections
Topic: Viral Infections
Topic: Viruses

 

Fill in the Blank Questions
 

  1. In humans, equine encephalitis can present as a spectrum from fever and headache to ___________ ____________and encephalitis.
    aseptic meningitis

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 2. Understand
Learning Outcome: 38.02.02 Identify typical signs and symptoms of two arthropod-borne viral diseases
Section: 38.02
Topic: Nervous System Infections
Topic: Viral Infections
Topic: Viruses

 

Multiple Choice Questions

  1. Which of the following does not transmit the AIDS virus?
    A. Semen
  2. Blood
  3. Vaginal secretions
  4. Mosquitoes

 

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 2. Understand
Learning Outcome: 38.03.01 Report the common viral diseases spread by direct contact
Section: 38.03
Topic: Systemic (Cardiovascular/Lymphatic) Infections
Topic: Viral Infections
Topic: Viruses

 

  1. Colds are common because
    A. domestic animals serve as a persistent reservoir.
    B.  immunity once obtained is not protective.
    C.  there is a lack of effective antiviral drugs.
    D.  of the antigenic diversity of the rhinoviruses and the lack of long-lasting immunity.

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 3. Apply
Learning Outcome: 38.01.01 Report the common viral diseases spread by airborne transmission
Section: 38.01
Topic: Respiratory System Infections
Topic: Viral Infections
Topic: Viruses

  1. Which of the following is known to activate the genital herpes virus?
    A. Sunlight
  2. Stress
  3. Sex hormones
  4. All of the choices are correct.

 

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 2. Understand
Learning Outcome: 38.03.02 Identify typical signs and symptoms of common viral diseases spread by direct contact
Learning Outcome: 38.03.03 Correlate direct contact virus infection and disease severity with viral virulence factors
Section: 38.03
Topic: Urogenital System Infections
Topic: Viral Infections
Topic: Viruses

 

  1. Which of the following is not associated with genital herpes?
    A. Congenital herpes
    B.  Cervical cancer
    C.  Miscarriages
    D.  Recurring genital lesions

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 2. Understand
Learning Outcome: 38.03.02 Identify typical signs and symptoms of common viral diseases spread by direct contact
Section: 38.03
Topic: Urogenital System Infections
Topic: Viral Infections
Topic: Viruses

  1. Large-scale screening of blood for the hepatitis B virus uses an assay designed to detect
    A.the Delta agent.
    B. the Dane particle.
    C. viral surface antigens.
    D. alanine transaminase.

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 2. Understand
Learning Outcome: 38.03.02 Identify typical signs and symptoms of common viral diseases spread by direct contact
Section: 38.03
Topic: Systemic (Cardiovascular/Lymphatic) Infections
Topic: Viral Infections
Topic: Viruses

 

  1. The leading reason for liver transplantation in the United States is _________.
    A. hepatitis C
    B.  hepatitis B
    C.  hepatitis A
    D.  hepatitis D

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 1. Remember
Learning Outcome: 38.03.02 Identify typical signs and symptoms of common viral diseases spread by direct contact
Section: 38.03
Topic: Systemic (Cardiovascular/Lymphatic) Infections
Topic: Viral Infections
Topic: Viruses

  1. Control measures for hepatitis B include
    A.excluding contact with contaminated materials.
    B. passive immunotherapy within 7 days of exposure.
    C. vaccination of high-risk groups.
    D.  All of the choices are correct.

 

 

ASM Objective: 03.04 The growth of microorganisms can be controlled by physical, chemical, mechanical, or biological methods.
ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 03 Metabolic Pathways
ASM Topic: Module 05 Microbial Systems
Blooms Level: 2. Understand
Learning Outcome: 38.03.02 Identify typical signs and symptoms of common viral diseases spread by direct contact
Section: 38.03
Topic: Gastrointestinal System Infections
Topic: Systemic (Cardiovascular/Lymphatic) Infections
Topic: Viral Infections
Topic: Viruses

 

  1. Which of the following can stimulate a reactivation of the virus that causes cold sores?
    A.Physical stress (fever, cold winds, trauma, hormonal changes)
  2. Emotional stress
  3. Ultraviolet light
  4. All of the choices are correct.

 

 

ASM Objective: 04.04 The synthesis of viral genetic material and proteins is dependent on host cells.
ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 04 Information Flow and Genetics
ASM Topic: Module 05 Microbial Systems
Blooms Level: 2. Understand
Learning Outcome: 38.03.02 Identify typical signs and symptoms of common viral diseases spread by direct contact
Section: 38.03
Topic: Skin/Skeletal Infections
Topic: Viral Infections
Topic: Viruses

 

  1. Which of the following is the typical mode of transmission for hepatitis C?
    A. Contaminated blood and blood products
  2. Inhalation of droplets
  3. Bite from body louse
  4. Contaminated shellfish

 

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 2. Understand
Learning Outcome: 38.03.02 Identify typical signs and symptoms of common viral diseases spread by direct contact
Section: 38.03
Topic: Systemic (Cardiovascular/Lymphatic) Infections
Topic: Viral Infections
Topic: Viruses

 

  1. Which of the following drugs is (are) effective against cold sores?
    A. Valcyclovir and acyclovir
  2. Amantadine
  3. AZT and ddC
    D. Protease inhibitors such as ritonavir

 

 

ASM Objective: 03.04 The growth of microorganisms can be controlled by physical, chemical, mechanical, or biological methods.
ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 03 Metabolic Pathways
ASM Topic: Module 05 Microbial Systems
Blooms Level: 1. Remember
Learning Outcome: 38.03.02 Identify typical signs and symptoms of common viral diseases spread by direct contact
Section: 38.03
Topic: Antivirals
Topic: Skin/Skeletal Infections
Topic: Viral Infections
Topic: Viruses

 

  1. Acyclovir is the drug used to treat genital herpes; it
    A.cures the disease.
    B. reduces the healing time.
    C. lyses the virus.
    D. All of the choices are correct

 

 

ASM Objective: 03.04 The growth of microorganisms can be controlled by physical, chemical, mechanical, or biological methods.
ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 03 Metabolic Pathways
ASM Topic: Module 05 Microbial Systems
Blooms Level: 2. Understand
Learning Outcome: 38.03.02 Identify typical signs and symptoms of common viral diseases spread by direct contact
Section: 38.03
Topic: Antivirals
Topic: Skin/Skeletal Infections
Topic: Viral Infections
Topic: Viruses

 

  1. Which of the following is correct about the protease inhibitor drugs designed to treat HIV infection?
    A.They slow the progress of the disease
  2. They cure the disease
  3. They prevent entry of the virus into cells
  4. They result in lysis of virus particles

 

 

ASM Objective: 03.04 The growth of microorganisms can be controlled by physical, chemical, mechanical, or biological methods.
ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 03 Metabolic Pathways
ASM Topic: Module 05 Microbial Systems
Blooms Level: 2. Understand
Learning Outcome: 38.03.02 Identify typical signs and symptoms of common viral diseases spread by direct contact
Section: 38.03
Topic: Antivirals
Topic: Systemic (Cardiovascular/Lymphatic) Infections
Topic: Viral Infections
Topic: Viruses

 

True / False Questions
 

  1. Hepatitis can be caused by cytomegalovirus and Epstein-Barr virus as well as by the hepatitis viruses.
    TRUE

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 1. Remember
Learning Outcome: 38.03.01 Report the common viral diseases spread by direct contact
Section: 38.03
Topic: Gastrointestinal System Infections
Topic: Systemic (Cardiovascular/Lymphatic) Infections
Topic: Viral Infections
Topic: Viruses

  1. The Epstein-Barr virus is the etiologic agent of infectious mononucleosis.
    TRUE

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 2. Understand
Learning Outcome: 38.03.01 Report the common viral diseases spread by direct contact
Section: 38.03
Topic: Systemic (Cardiovascular/Lymphatic) Infections
Topic: Viral Infections
Topic: Viruses

  1. Antiviral drugs are frequently used for the treatment of infectious mononucleosis.
    FALSE

 

ASM Objective: 03.04 The growth of microorganisms can be controlled by physical, chemical, mechanical, or biological methods.
ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 03 Metabolic Pathways
ASM Topic: Module 05 Microbial Systems
Blooms Level: 2. Understand
Learning Outcome: 38.03.02 Identify typical signs and symptoms of common viral diseases spread by direct contact
Section: 38.03
Topic: Systemic (Cardiovascular/Lymphatic) Infections
Topic: Viral Infections
Topic: Viruses

 

  1. The formation of intranuclear inclusion bodies is associated with cytomegalovirus infection.
    TRUE

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 1. Remember
Learning Outcome: 38.03.02 Identify typical signs and symptoms of common viral diseases spread by direct contact
Learning Outcome: 38.03.03 Correlate direct contact virus infection and disease severity with viral virulence factors
Section: 38.03
Topic: Systemic (Cardiovascular/Lymphatic) Infections
Topic: Viral Infections
Topic: Viruses

  1. Warts or verrucae are caused by the papillomaviruses.
    TRUE

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 1. Remember
Learning Outcome: 38.03.02 Identify typical signs and symptoms of common viral diseases spread by direct contact
Learning Outcome: 38.03.03 Correlate direct contact virus infection and disease severity with viral virulence factors
Section: 38.03
Topic: Skin/Skeletal Infections
Topic: Viral Infections
Topic: Viruses

  1. Plantar warts represent a sexually transmitted disease.
    FALSE

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 1. Remember
Learning Outcome: 38.03.02 Identify typical signs and symptoms of common viral diseases spread by direct contact
Section: 38.03
Topic: Skin/Skeletal Infections
Topic: Viral Infections
Topic: Viruses

 

  1. The most likely mode of transmission of the common cold is by hand-to-hand contact between a rhinovirus donor and a susceptible recipient.
    TRUE

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 1. Remember
Learning Outcome: 38.01.02 Identify typical signs and symptoms of viral diseases spread by airborne transmission
Learning Outcome: 38.03.02 Identify typical signs and symptoms of common viral diseases spread by direct contact
Section: 38.01
Section: 38.03
Topic: Respiratory System Infections
Topic: Viral Infections
Topic: Viruses

  1. Coinfection with HIV and Human Herpesvirus 8 (HHV-8) can greatly promote the development of cancer in AIDS patients.
    TRUE

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 2. Understand
Learning Outcome: 38.03.01 Report the common viral diseases spread by direct contact
Learning Outcome: 38.03.02 Identify typical signs and symptoms of common viral diseases spread by direct contact
Section: 38.03
Topic: Systemic (Cardiovascular/Lymphatic) Infections
Topic: Urogenital System Infections
Topic: Viral Infections
Topic: Viruses

 

Fill in the Blank Questions

  1. The AIDS virus becomes established in cells bearing the __________ receptor.
    CD4

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 1. Remember
Learning Outcome: 38.03.02 Identify typical signs and symptoms of common viral diseases spread by direct contact
Section: 38.03
Topic: Systemic (Cardiovascular/Lymphatic) Infections
Topic: Viral Infections

 

  1. A type of cancer associated with AIDS is __________ sarcoma.

Kaposi’s

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 1. Remember
Learning Outcome: 38.03.02 Identify typical signs and symptoms of common viral diseases spread by direct contact
Section: 38.03
Topic: Retroviruses
Topic: Systemic (Cardiovascular/Lymphatic) Infections
Topic: Viral Infections
Topic: Viruses

  1. Cold sores or fever blisters are caused by the ________ ________ virus.
    herpes simplex

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 1. Remember
Learning Outcome: 38.03.01 Report the common viral diseases spread by direct contact
Section: 38.03
Topic: Skin/Skeletal Infections
Topic: Viral Infections
Topic: Viruses

  1. A major cause of blindness in the United States that results from the HSV 1 virus is ___________ ___________.
    herpetic keratitis

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 2. Understand
Learning Outcome: 38.03.02 Identify typical signs and symptoms of common viral diseases spread by direct contact
Section: 38.03
Topic: Viral Infections
Topic: Viruses

 

Multiple Choice Questions
 

  1. Most drugs used to slow the progress of AIDS fall into which of the following categories?
    A. Reverse transcriptase and protease inhibitors
  2. Topoisomerase inhibitors
  3. RNA polymerase II inhibitors
    D. Protein synthesis inhibitors

 

 

ASM Objective: 03.04 The growth of microorganisms can be controlled by physical, chemical, mechanical, or biological methods.
ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 03 Metabolic Pathways
ASM Topic: Module 05 Microbial Systems
Blooms Level: 2. Understand
Learning Outcome: 38.03.02 Identify typical signs and symptoms of common viral diseases spread by direct contact
Section: 38.03
Topic: Antivirals
Topic: Systemic (Cardiovascular/Lymphatic) Infections
Topic: Viral Infections
Topic: Viruses

  1. The main route of transmission of the poliovirus is _________.
    A. body contact
    B.  fomites
    C.  food and water
    D.  respiratory secretions

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 1. Remember
Learning Outcome: 38.04.01 Report the common food-borne and waterborne viral diseases
Section: 38.04
Topic: Nervous System Infections
Topic: Viral Infections
Topic: Viruses

 

  1. Infectious hepatitis (hepatitis A) is usually transmitted by
    A.fecal-oral contamination of food or drink.
    B. sexual activity.
    C. contaminated blood.
    D. inhalation of droplets.

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 2. Understand
Learning Outcome: 38.04.01 Report the common food-borne and waterborne viral diseases
Section: 38.04
Topic: Gastrointestinal System Infections
Topic: Viral Infections
Topic: Viruses

  1. Acute viral gastroenteritis can be caused by the
    A.norovirus and the rotavirus group.
    B. cytomegalovirus and hepatitis E.
    C. the Delta agent.
    D. varicella zoster virus and rubeola virus.

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 1. Remember
Learning Outcome: 38.04.01 Report the common food-borne and waterborne viral diseases
Section: 38.04
Topic: Gastrointestinal System Infections
Topic: Viral Infections
Topic: Viruses

 

  1. Acute viral gastroenteritis is the leading cause of death in
    A.children worldwide.
    B.  children in the United.States.
  2. children in developing countries.
    D.children in day care centers.

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 1. Remember
Learning Outcome: 38.04.03 Correlate food-borne and waterborne virus infection and disease severity with viral virulence factors
Section: 38.04
Topic: Gastrointestinal System Infections
Topic: Viral Infections
Topic: Viruses

  1. Prevention and control of rabies includes
    A.pre-exposure vaccination of dogs and cats.
    B. post-exposure vaccination of humans.
    C. pre-exposure vaccination of humans at high risk.
    D.  All of the choices are correct.

 

 

ASM Objective: 03.04 The growth of microorganisms can be controlled by physical, chemical, mechanical, or biological methods.
ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 03 Metabolic Pathways
ASM Topic: Module 05 Microbial Systems
Blooms Level: 2. Understand
Learning Outcome: 38.05.01 Report the common viral diseases spread by contact with infected animals
Section: 38.05
Topic: Nervous System Infections
Topic: Viral Infections
Topic: Viruses

 

  1. The rabies virus is transmitted to humans by
    A.the bite of an infected animal.
    B. aerosols of the virus that can be present in caves where bats roost.
    C. contamination of scratches with saliva from an infected animal.
    D.  All of the choices are correct.

 

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 2. Understand
Learning Outcome: 38.05.01 Report the common viral diseases spread by contact with infected animals
Section: 38.05
Topic: Nervous System Infections
Topic: Viral Infections
Topic: Viruses

  1. Negri bodies are produced within  _______________ of rabies-infected humans.
    A. skeletal muscle
    B.  connective tissue
    C.  brain neurons
    D.  the skin

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 1. Remember
Learning Outcome: 38.05.02 Identify typical signs and symptoms of zoonotic viral diseases
Learning Outcome: 38.05.03 Correlate zoonotic virus infection and disease severity with viral attachment factors
Section: 38.05
Topic: Nervous System Infections
Topic: Viral Infections
Topic: Viruses

 

  1. Who should be vaccinated against rabies?
    A. Nurses
    B.  Farmers
    C.  Veterinarians
    D.  Physicians

 

ASM Objective: 03.04 The growth of microorganisms can be controlled by physical, chemical, mechanical, or biological methods.
ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 03 Metabolic Pathways
ASM Topic: Module 05 Microbial Systems
Blooms Level: 2. Understand
Learning Outcome: 38.05.02 Identify typical signs and symptoms of zoonotic viral diseases
Section: 38.05
Topic: Nervous System Infections
Topic: Viral Infections
Topic: Viruses

  1. The Ebola virus causes _________.
    A. encephalitis
    B.  pulmonary syndrome
    C.  hemorrhagic fever
    D.  lassa fever

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 1. Remember
Learning Outcome: 38.05.01 Report the common viral diseases spread by contact with infected animals
Section: 38.05
Topic: Systemic (Cardiovascular/Lymphatic) Infections
Topic: Viral Infections
Topic: Viruses

 

  1. Which of the following is a disease of humans that is probably caused by a prion and was originally associated with cannibalism?
    A.Gerstmann-Sträussler-Scheinker disease
    B. Creutzfeld-Jakob disease
    C.  Kuru
  2. Gerstmann-Sträussler-Scheinker and Creutzfeld-Jakob diseases
  3. Both Creutzfeld-Jakob disease and kuru
  4. Both Gerstmann-Sträussler-Scheinker disease and kuru

 

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 1. Remember
Learning Outcome: 38.06.01 Describe diseases caused by prions
Learning Outcome: 38.06.02 Differentiate prion disease by route of infection
Section: 38.06
Topic: Prions

  1. Iatrogenic CJD has been transmitted by all of the following EXCEPT
    A. human growth hormone.
    B.  corneal grafts.
    C.  liver transplants.
    D.  grafts of dura mater.

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 2. Understand
Learning Outcome: 38.06.02 Differentiate prion disease by route of infection
Section: 38.06
Topic: Prions

 

 

 

True / False Questions

  1. One hundred fifty one deaths have been attributed to vCJD in the United.States.
    FALSE

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 2. Understand
Learning Outcome: 38.06.01 Describe diseases caused by prions
Section: 38.06
Topic: Prions

 

Multiple Choice Questions

  1. A traveler returning to the United.States from India reported having a fever and severe joint pain. She mentioned that the mosquitoes had been particularly troublesome during her trip, and that she had taken the appropriate prophylactic anti-malarial medications. What is a likely cause of her illness?
    A. Malaria
    B.  Yellow fever
    C.  Lyme disease
    D.  West Nile virus
    E.  Chickungunya fever

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 4. Analyze
Learning Outcome: 38.02.01 Report the two common arthropod-borne viral diseases
Learning Outcome: 38.02.02 Identify typical signs and symptoms of two arthropod-borne viral diseases
Learning Outcome: 38.02.03 Correlate arthropod-borne virus infection with geography and time of year
Section: 38.02
Topic: Arthropod Vectors
Topic: Viral Infections
Topic: Viruses

 

  1. Consider the possibility of a mutation occurring in a strain of avian influenza virus which enables the bird-specific strain to readily infect humans. Such a mutation would most likely result in changes within the _________.
    A. viral capsid
    B.  RNA-dependent RNA polymerase
    C.  HA protein
    D.  nucleoprotein (NP)

 

ASM Objective: 04.01 Genetic variations can impact microbial functions (e.g., in biofilm formation, pathogenicity and drug resistance).
ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 04 Information Flow and Genetics
ASM Topic: Module 05 Microbial Systems
Blooms Level: 4. Analyze
Learning Outcome: 38.01.03 Correlate airborne viral infection and disease severity with viral virulence factors
Section: 38.01
Topic: Respiratory System Infections
Topic: Viral Infections
Topic: Viruses

  1. What critical role is often played by pigs in the epidemiology of influenza virus?
    A. Pigs are the reservoir for influenza virus and most humans become infected by contact with respiratory secretions of pigs.
    B.  Pigs are the reservoir for influenza viruses and disease can be transmitted to humans by consuming undercooked pork.
    C.  Pigs can become infected simultaneously with both human, avian, and swine varieties of influenza viruses, providing an opportunity for genetic recombination resulting in antigenic drift.
    D.  Pigs harbor influenza viruses that are much more virulent than avian strains and human strains.

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 4. Analyze
Learning Outcome: 38.01.03 Correlate airborne viral infection and disease severity with viral virulence factors
Section: 38.01
Topic: Respiratory System Infections
Topic: Viral Infections
Topic: Viruses

 

  1. A researcher is attempting to determine the prevalence of asymptomatic human infection  with West Nile virus in New York City. Which of the following would be most useful?
    A. Tissue culture
    B.  Electron microscopy
    C.  Detection of IgG against WNV
    D.  Detection of IgM against WNV
    E.  Viral culture in embryonated eggs

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 4. Analyze
Learning Outcome: 38.02.02 Identify typical signs and symptoms of two arthropod-borne viral diseases
Learning Outcome: 38.02.03 Correlate arthropod-borne virus infection with geography and time of year
Section: 38.02
Topic: Arthropod Vectors
Topic: Nervous System Infections
Topic: Viral Infections
Topic: Viruses

 

True / False Questions

  1. Arthropod-borne encephalitis would show less seasonality in a tropical or subtropical climate than what is seen in a temperate climate.
    TRUE

 

ASM Objective: 05.03 Microorganisms and their environment interact with and modify each other.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 4. Analyze
Learning Outcome: 38.02.03 Correlate arthropod-borne virus infection with geography and time of year
Section: 38.02
Topic: Arthropod Vectors
Topic: Nervous System Infections
Topic: Viral Infections

 

  1. Most cases of viral gastroenteritis are accompanied by high fevers.
    FALSE

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 2. Understand
Learning Outcome: 38.04.02 Identify typical signs and symptoms of common food-borne and waterborne viral diseases
Section: 38.04
Topic: Gastrointestinal System Infections
Topic: Viral Infections
Topic: Viruses

 

Multiple Choice Questions

  1. Which of the following is the most notable symptom of infection with Norovirus?
    A. Vomiting
    B.  Headache
    C.  Fever
    D.  Constipation
    E.  Skin rash

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 4. Analyze
Learning Outcome: 38.04.02 Identify typical signs and symptoms of common food-borne and waterborne viral diseases
Section: 38.04
Topic: Gastrointestinal System Infections
Topic: Viral Infections

 

  1. Which of the following is the most common outcome of infection with polio virus?
    A. Paralysis of the lower extremities
    B.  Paralysis involving the muscles that enable respiration
    C.  Severe gastrointestinal disease with vomiting and diarrhea
    D.  Mild infection with fever, headacheRemember,re throat, or asymptomatic

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 3. Apply
Learning Outcome: 38.04.03 Correlate food-borne and waterborne virus infection and disease severity with viral virulence factors
Section: 38.04
Topic: Gastrointestinal System Infections
Topic: Nervous System Infections
Topic: Viral Infections

 

Check All That Apply Questions

  1. What characteristics of polio virus and infection make it possible that this disease will likely be eradicated?  Check all that apply.
    __X__  Polio virus has no animal reservoirs.
    __X__  There is an effective vaccine that prevents polio.
    _____  There is effective antiviral therapy for polio infection.

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 4. Analyze
Learning Outcome: 38.04.03 Correlate food-borne and waterborne virus infection and disease severity with viral virulence factors
Section: 38.04
Topic: Gastrointestinal System Infections
Topic: Nervous System Infections
Topic: Viral Infections

 

Multiple Choice Questions
 

  1. What is the most likely reason why Reston ebolavirus does not cause human disease?
    A. The human body temperature prohibits viral replication.
    B.  Human tissues lack the appropriate receptors for this viral strain.
    C.  Humans have antibodies that prevent establishment of infection with this viral strain.
    D.  Human interferons prevent the establishment of infection with this viral.

 

ASM Objective: 03.03 The survival and growth of any microorganism in a given environment depends on its metabolic characteristics.
ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 03 Metabolic Pathways
ASM Topic: Module 05 Microbial Systems
Blooms Level: 4. Analyze
Learning Outcome: 38.05.03 Correlate zoonotic virus infection and disease severity with viral attachment factors
Section: 38.05
Topic: Viral Infections

  1. What is the most likely reason that bats, raccoons, and foxes readily become infected with the rabies virus, whereas opossums are resistant to infection?
    A. The rabies virus is unable to replicate once it has entered the opossum cells.
    B.  Infected opossums do not shed rabies virus in their saliva.
    C.  Opossums lack the appropriate receptor for the rabies virus.
    D.  Opossums rarely contact other infected animals.

 

ASM Objective: 05.04 Microorganisms, cellular and viral, can interact with both human and nonhuman hosts in beneficial, neutral or detrimental ways.
ASM Topic: Module 05 Microbial Systems
Blooms Level: 4. Analyze
Learning Outcome: 38.05.02 Identify typical signs and symptoms of zoonotic viral diseases
Learning Outcome: 38.05.03 Correlate zoonotic virus infection and disease severity with viral attachment factors
Section: 38.05
Topic: Nervous System Infections
Topic: Viral Infections

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